PMID- 25303625 OWN - NLM STAT- MEDLINE DCOM- 20161110 LR - 20171116 IS - 1447-0756 (Electronic) IS - 1341-8076 (Linking) VI - 41 IP - 3 DP - 2015 Mar TI - Ewing's sarcoma/peripheral primitive neuroectodermal tumors of the uterus confirmed with fluorescence in situ hybridization in a 29-year-old Chinese female: a case report and published work review. PG - 478-82 LID - 10.1111/jog.12552 [doi] AB - Ewing's sarcoma/peripheral primitive neuroectodermal tumors (ES/pPNET) are a group of small round cell sarcomas that show varying degrees of neuroectodermal differentiation characterized by translocation involving the EWS gene. Uterine ES/pPNET is a rare entity. A 29-year-old Chinese female who presented with abdominal swelling and pain was diagnosed with a primary uterine ES/pPNET on the basis of clinicopathologic, immunohistochemical and fluorescence in situ hybridization (FISH) data. She was given a multimodal treatment, including neoadjuvant, 95% cytoreductive, chemotherapy and radiotherapy. The patient is currently alive with persistent disease after 18 months of follow-up. We emphasized the crucial role of molecular techniques in the differential diagnosis of small round cell tumors in this unusual location. Multimodal therapy may improve the outcomes of patients. CI - (c) 2014 The Authors. Journal of Obstetrics and Gynaecology Research (c) 2014 Japan Society of Obstetrics and Gynecology. FAU - Yi, Tianjin AU - Yi T AD - Department of Gynecology, West China Second University Hospital of Sichuan University, Chengdu, China. FAU - Wang, Ping AU - Wang P FAU - Lin, Lin AU - Lin L FAU - Jiang, Wei AU - Jiang W LA - eng PT - Case Reports PT - Journal Article PT - Review DEP - 20141010 PL - Australia TA - J Obstet Gynaecol Res JT - The journal of obstetrics and gynaecology research JID - 9612761 RN - 0 (Calmodulin-Binding Proteins) RN - 0 (EWSR1 protein, human) RN - 0 (RNA-Binding Protein EWS) RN - 0 (RNA-Binding Proteins) SB - IM MH - Adult MH - Calmodulin-Binding Proteins/*genetics MH - Female MH - Humans MH - In Situ Hybridization, Fluorescence MH - Neuroectodermal Tumors, Primitive, Peripheral/*diagnosis/genetics MH - RNA-Binding Protein EWS MH - RNA-Binding Proteins/*genetics MH - Sarcoma, Ewing/*diagnosis/genetics MH - Uterine Neoplasms/*diagnosis/genetics OTO - NOTNLM OT - Ewing's sarcoma/peripheral primitive neuroectodermal tumors OT - fluorescence in situ hybridization OT - multimodal therapy OT - uterus EDAT- 2014/10/11 06:00 MHDA- 2016/11/12 06:00 CRDT- 2014/10/11 06:00 PHST- 2014/05/09 00:00 [received] PHST- 2014/07/29 00:00 [accepted] PHST- 2014/10/11 06:00 [entrez] PHST- 2014/10/11 06:00 [pubmed] PHST- 2016/11/12 06:00 [medline] AID - 10.1111/jog.12552 [doi] PST - ppublish SO - J Obstet Gynaecol Res. 2015 Mar;41(3):478-82. doi: 10.1111/jog.12552. Epub 2014 Oct 10.