PMID- 25305070 OWN - NLM STAT- MEDLINE DCOM- 20150316 LR - 20220408 IS - 1557-8615 (Electronic) IS - 0883-9441 (Linking) VI - 30 IP - 1 DP - 2015 Feb TI - Single-center large-cohort study into quality of life in Dutch intensive care unit subgroups, 1 year after admission, using EuroQoL EQ-6D-3L. PG - 181-6 LID - S0883-9441(14)00387-6 [pii] LID - 10.1016/j.jcrc.2014.09.009 [doi] AB - PURPOSE: The goal of this study was to describe long-term survival and health-related quality of life (HRQoL), measured by EQ-6D, in a general intensive care unit (ICU) population. MATERIALS AND METHODS: We included 5934 consecutive adult patients admitted to a mixed-population ICU. There were no exclusion criteria. One-year survival status was determined using the Dutch municipal population register. Subsequently, all survivors received the EuroQoL EQ-6D-3L questionnaire. The primary outcome was overall HRQoL and survival of the ICU survivors, compared to overall QoL of an age- and sex-matched reference population. RESULTS: A total of 5138 patients (86.6%) survived until hospital discharge, with 4647 (78.3%) patients surviving the 1-year of follow-up. The EuroQoL questionnaire was sent to 4465 survivors and returned by 3034 (68.0%) of 4465. The median HRQoL in surviving patients was 0.83 (interquartile range [IQR], 0.64-1.00) vs 0.86 (IQR, 0.85-0.86) in the reference population (P < .001). There was marked variation across admission diagnosis groups: cardiac surgery patients had an HRQoL of 0.94 (IQR, 0.74-1.00), whereas patients admitted with chronic renal failure had an HRQoL of 0.65 (IQR, 0.47-0.83). CONCLUSIONS: One year after ICU admission, HRQoL was significantly lower than in the reference population. Notably, marked variations were found across subgroups. CI - Copyright (c) 2014 Elsevier Inc. All rights reserved. FAU - Soliman, Ivo W AU - Soliman IW AD - Department of Intensive Care Medicine, University Medical Centre Utrecht, Utrecht, the Netherlands. Electronic address: I.W.Soliman@umcutrecht.nl. FAU - de Lange, Dylan W AU - de Lange DW AD - Department of Intensive Care Medicine, University Medical Centre Utrecht, Utrecht, the Netherlands. FAU - Peelen, Linda M AU - Peelen LM AD - Department of Intensive Care Medicine, University Medical Centre Utrecht, Utrecht, the Netherlands. FAU - Cremer, Olaf L AU - Cremer OL AD - Department of Intensive Care Medicine, University Medical Centre Utrecht, Utrecht, the Netherlands. FAU - Slooter, Arjen J C AU - Slooter AJ AD - Department of Intensive Care Medicine, University Medical Centre Utrecht, Utrecht, the Netherlands. FAU - Pasma, Wietze AU - Pasma W AD - Department of Intensive Care Medicine, University Medical Centre Utrecht, Utrecht, the Netherlands. FAU - Kesecioglu, Jozef AU - Kesecioglu J AD - Department of Intensive Care Medicine, University Medical Centre Utrecht, Utrecht, the Netherlands. FAU - van Dijk, Diederik AU - van Dijk D AD - Department of Intensive Care Medicine, University Medical Centre Utrecht, Utrecht, the Netherlands. LA - eng PT - Journal Article DEP - 20140922 PL - United States TA - J Crit Care JT - Journal of critical care JID - 8610642 SB - IM MH - APACHE MH - Aged MH - Cohort Studies MH - Critical Care/*statistics & numerical data MH - Critical Illness/*mortality MH - Female MH - Health Surveys/methods MH - Hospital Mortality MH - *Hospitalization MH - Humans MH - Intensive Care Units/*statistics & numerical data MH - Length of Stay MH - Male MH - Middle Aged MH - Netherlands MH - Patient Discharge MH - *Quality of Life MH - Surveys and Questionnaires MH - Survival Analysis MH - *Survivors MH - Time Factors OTO - NOTNLM OT - Critical care OT - EuroQoL OT - Health-related quality of life OT - Intensive care OT - Long term OT - Quality of life EDAT- 2014/10/12 06:00 MHDA- 2015/03/17 06:00 CRDT- 2014/10/12 06:00 PHST- 2014/02/03 00:00 [received] PHST- 2014/09/02 00:00 [revised] PHST- 2014/09/09 00:00 [accepted] PHST- 2014/10/12 06:00 [entrez] PHST- 2014/10/12 06:00 [pubmed] PHST- 2015/03/17 06:00 [medline] AID - S0883-9441(14)00387-6 [pii] AID - 10.1016/j.jcrc.2014.09.009 [doi] PST - ppublish SO - J Crit Care. 2015 Feb;30(1):181-6. doi: 10.1016/j.jcrc.2014.09.009. Epub 2014 Sep 22.