PMID- 2531022
OWN - NLM
STAT- MEDLINE
DCOM- 19900103
LR  - 20151119
IS  - 0037-9026 (Print)
IS  - 0037-9026 (Linking)
VI  - 183
IP  - 2
DP  - 1989
TI  - [TRH dissociates the aggressivity of vegetative and motor phenomena induced by 
      carbachol in the cat].
PG  - 148-52
AB  - In these experiments interaction of thyrotropin releasing hormone (TRH) and 
      carbachol injected into the cerebral ventricles of unanaesthetized cats has been 
      investigated. Intracerebroventricular (i.c.v.) carbachol as well as i.c.v. TRH 
      produced emotional behaviour, autonomic and motor phenomena. The most impressive 
      feature of i.c.v. carbachol was the aggressive behaviour, whereas that of i.c.v. 
      TRH the autonomic changes. In cats treated with i.c.v. TRH, the aggressive 
      behaviour, but the autonomic and motor changes of i.c.v. carbachol was 
      potentiated. Since there is evidence that carbachol acts mainly on muscarinic M-2 
      receptors, the potentiation by TRH of aggressive behaviour, but not the autonomic 
      and motor changes induced by carbachol could indicate heterogeneity of central 
      muscarinic M-2 receptors.
FAU - Samardzic, R
AU  - Samardzic R
AD  - Institut de Pharmacologie, Faculte de Medecine, Belgrade, Yougoslavie.
FAU - Jovanovic-Micic, D
AU  - Jovanovic-Micic D
FAU - Beleslin, D
AU  - Beleslin D
LA  - fre
PT  - English Abstract
PT  - Journal Article
TT  - La TRH dissocie l'agressivite des phenomenes vegetatifs et moteurs induits par le 
      carbachol chez le chat.
PL  - France
TA  - C R Seances Soc Biol Fil
JT  - Comptes rendus des seances de la Societe de biologie et de ses filiales
JID - 7505439
RN  - 5Y5F15120W (Thyrotropin-Releasing Hormone)
RN  - 8Y164V895Y (Carbachol)
SB  - IM
MH  - Aggression/*drug effects
MH  - Animals
MH  - Behavior, Animal/*drug effects
MH  - Carbachol/administration & dosage/*pharmacology
MH  - Cats
MH  - Drug Interactions
MH  - Female
MH  - Injections, Intraventricular
MH  - Male
MH  - Motor Activity/*drug effects
MH  - Thyrotropin-Releasing Hormone/administration & dosage/*pharmacology
EDAT- 1989/01/01 00:00
MHDA- 1989/01/01 00:01
CRDT- 1989/01/01 00:00
PHST- 1989/01/01 00:00 [pubmed]
PHST- 1989/01/01 00:01 [medline]
PHST- 1989/01/01 00:00 [entrez]
PST - ppublish
SO  - C R Seances Soc Biol Fil. 1989;183(2):148-52.