PMID- 25310435
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20141015
LR  - 20141014
IS  - 0103-507X (Print)
IS  - 0103-507X (Linking)
VI  - 18
IP  - 3
DP  - 2006 Sep
TI  - [Stress ulcer prophylaxis in intensive care units: an observational multicenter 
      study].
PG  - 229-33
LID - S0103-507X2006000300003 [pii]
AB  - BACKGROUND AND OBJECTIVES: Gastrointestinal bleeding due to stress ulcer (GB) 
      complicates critical disease, and must be received prophylaxis based on defined 
      criteria. To evaluate the GB prophylaxis in Intensive Care Units (ICU), and to 
      compare with the guidelines. METHODS: We carried out a cross-sectional 
      multicenter study in 21 medical-surgical ICU in Brazil to investigate this issue. 
      For data analysis, these were distributed in 3 sub-groups (high, moderate and low 
      risk for GB). RESULTS: 235 patients were evaluated, with mean age of 57.7 +/- 19.5 
      years and days on ICU 13 +/- 19.7. The more common admission ICU diagnoses were 
      sepsis (26%) and postoperative (16.2%) patients. Seventy-three (73%) of the 
      patients were GB high risk, 21.5% moderate and 5.5% low risk. Of the 187 high 
      risk patients, 139 were receiving GB prophylaxis (60% with histamine blockers 
      (HB2) and 39% with proton pump inhibitors (PPI). Of these patients, 25.7% did not 
      receive GU prophylaxis, although indicated it. Of the 55 moderate risk patients, 
      70.9% wer e receiving GU prophylaxis (22 with HB2 and 17 with PPI). Of the 14 low 
      risk patients, 71% were using GU prophylaxis (6 with HB2 and 4 with PPI). 
      CONCLUSIONS: Almost 80% of the patients made use of GB prophylactic drugs, with 
      no agreement GU risk stratification. This study demonstrated the no adequate GU 
      prophylaxis in the Brazilian ICU.
FAU - Machado, Andre Sant'Ana
AU  - Machado AS
AD  - Hospital Moinhos de Vento de Porto Alegre.
FAU - Teixeira, Cassiano
AU  - Teixeira C
AD  - Hospital Moinhos de Vento de Porto Alegre.
LA  - por
PT  - English Abstract
PT  - Journal Article
TT  - Profilaxia para ulcera de estresse nas unidades de terapia intensiva: estudo 
      observacional multicentrico.
PL  - Brazil
TA  - Rev Bras Ter Intensiva
JT  - Revista Brasileira de terapia intensiva
JID - 9506692
EDAT- 2006/09/01 00:00
MHDA- 2006/09/01 00:01
CRDT- 2014/10/14 06:00
PHST- 2006/05/20 00:00 [received]
PHST- 2006/08/31 00:00 [accepted]
PHST- 2014/10/14 06:00 [entrez]
PHST- 2006/09/01 00:00 [pubmed]
PHST- 2006/09/01 00:01 [medline]
AID - S0103-507X2006000300003 [pii]
PST - ppublish
SO  - Rev Bras Ter Intensiva. 2006 Sep;18(3):229-33.