PMID- 25312979
OWN - NLM
STAT- MEDLINE
DCOM- 20150615
LR  - 20191113
IS  - 2212-3946 (Electronic)
IS  - 1574-888X (Linking)
VI  - 9
IP  - 6
DP  - 2014
TI  - A comprehensive review on perfusion method development for bone marrow collection 
      and stem cell transplantation.
PG  - 522-5
AB  - Bone marrow transplant (BMT) is done by the replacement of damaged bone marrow 
      with healthy one. These healthy bone marrow cells (BMCs) are usually collected 
      from the crest of the Ilium in humans hence these cells are used to replace 
      damaged ones in the treatment of bone marrow related diseases such as leukemia, 
      aplastic anemia, congenital immunodeficiency and autoimmune diseases. Even though 
      there are different methods, perfusion method is one of the simple, safe and less 
      contaminated methods used to harvest BMCs and it can reduce the risk in allogenic 
      BMT. Intra bone marrow-bone marrow transfer (IBM-BMT) is one of the best 
      procedures for allogenic BMT. Due to enlisting of hematopoietic stem cells and 
      mesenchymal stem cells, which are derived from donor, this method has 
      distinguishable advantages in allogenic BMT. In this paper the perfusion method 
      (for harvesting BMCs) and IBM-BMT (for their transplantation) have been 
      critically reviewed and showed that both methods are together will become an 
      effective combination in allogeneic BMT.
FAU - Korrapati, Narasimhulu
AU  - Korrapati N
FAU - Nanganuru, Harikrishna Y
AU  - Nanganuru HY
AD  - Department of Biotechnology, National Institute of Technology Warangal, 
      Warangal-506004, India. simha7762006@gmail.com.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United Arab Emirates
TA  - Curr Stem Cell Res Ther
JT  - Current stem cell research & therapy
JID - 101272517
SB  - IM
MH  - Allografts
MH  - Animals
MH  - Bone Marrow Cells/cytology
MH  - Bone Marrow Transplantation/*methods
MH  - Humans
MH  - Perfusion
MH  - Stem Cell Transplantation/*methods
EDAT- 2014/10/15 06:00
MHDA- 2015/06/16 06:00
CRDT- 2014/10/15 06:00
PHST- 2014/03/11 00:00 [received]
PHST- 2014/03/19 00:00 [revised]
PHST- 2014/03/19 00:00 [accepted]
PHST- 2014/10/15 06:00 [entrez]
PHST- 2014/10/15 06:00 [pubmed]
PHST- 2015/06/16 06:00 [medline]
AID - CSCRT-62589 [pii]
AID - 10.2174/1574888x0906140930110950 [doi]
PST - ppublish
SO  - Curr Stem Cell Res Ther. 2014;9(6):522-5. doi: 10.2174/1574888x0906140930110950.