PMID- 25316719
OWN - NLM
STAT- MEDLINE
DCOM- 20150106
LR  - 20220408
IS  - 1552-5783 (Electronic)
IS  - 0146-0404 (Linking)
VI  - 55
IP  - 11
DP  - 2014 Oct 14
TI  - Macular measurements using spectral-domain optical coherence tomography in 
      Chinese myopic children.
PG  - 7410-6
LID - 10.1167/iovs.14-13894 [doi]
AB  - PURPOSE: To evaluate the macular thickness/volume in Chinese myopic children 
      using spectral-domain optical coherence tomography (SD-OCT) and assess its 
      correlation with spherical equivalent refraction (SER), axial length (AL), sex, 
      and age. METHODS: A total of 194 eyes from 194 children (aged 6-17 years old) 
      with emmetropia (-0.5 diopters [D] < SER </= 0.5 D), low myopia (-3.0 D < SER </= 
      -0.5 D), and moderate to high myopia (SER </= -3.0 D) were recruited in the study. 
      Each child underwent standardized ophthalmic examinations including visual acuity 
      (VA), cycloplegic refraction, and AL measurement. The macular thickness for the 
      nine Early Treatment Diabetic Retinopathy Study (ETDRS) regions and the average 
      macular thickness/volume were measured and calculated. RESULTS: Analyses of 
      macular thickness for the ETDRS regions showed that the fovea was the thinnest of 
      the nine regions, followed by the outer ring; the inner ring was the thickest. 
      When compared to children with emmetropia or low myopia, children with moderate 
      to high myopia tended to have greater foveal thickness, thinner quadrant-specific 
      thickness in the outer ring, and smaller average macular thickness/volume. Also, 
      there were significant differences in foveal, superior outer, inferior outer, and 
      temporal outer quadrants among lowest, middle, and highest AL groups. Boys were 
      found to have greater macular thickness than girls in fovea and inner ring 
      regions. CONCLUSIONS: Our study highlights the variations and sex differences of 
      macular thickness/volume in Chinese myopic children using SD-OCT.
CI  - Copyright 2014 The Association for Research in Vision and Ophthalmology, Inc.
FAU - Chen, Si
AU  - Chen S
AD  - Department of Ophthalmology, Beijing Shijitan Hospital, Capital University of 
      Medical Sciences, Peking, People's Republic of China.
FAU - Wang, Bingsong
AU  - Wang B
AD  - Department of Ophthalmology, Beijing Shijitan Hospital, Capital University of 
      Medical Sciences, Peking, People's Republic of China.
FAU - Dong, Ning
AU  - Dong N
AD  - Department of Ophthalmology, Beijing Shijitan Hospital, Capital University of 
      Medical Sciences, Peking, People's Republic of China.
FAU - Ren, Xiaofang
AU  - Ren X
AD  - Department of Ophthalmology, Beijing Shijitan Hospital, Capital University of 
      Medical Sciences, Peking, People's Republic of China.
FAU - Zhang, Tuohong
AU  - Zhang T
AD  - School of Public Health, Peking University, Peking, People's Republic of China.
FAU - Xiao, Lin
AU  - Xiao L
AD  - Department of Ophthalmology, Beijing Shijitan Hospital, Capital University of 
      Medical Sciences, Peking, People's Republic of China.
LA  - eng
PT  - Journal Article
DEP - 20141014
PL  - United States
TA  - Invest Ophthalmol Vis Sci
JT  - Investigative ophthalmology & visual science
JID - 7703701
SB  - IM
MH  - Adolescent
MH  - Child
MH  - China/epidemiology
MH  - Female
MH  - Humans
MH  - Macula Lutea/*pathology
MH  - Male
MH  - Myopia/*diagnosis/epidemiology/physiopathology
MH  - Prevalence
MH  - *Refraction, Ocular
MH  - Retrospective Studies
MH  - Tomography, Optical Coherence/*methods
OTO - NOTNLM
OT  - myopia
OT  - optical coherence tomography
OT  - refractive error
EDAT- 2014/10/16 06:00
MHDA- 2015/01/07 06:00
CRDT- 2014/10/16 06:00
PHST- 2014/10/16 06:00 [entrez]
PHST- 2014/10/16 06:00 [pubmed]
PHST- 2015/01/07 06:00 [medline]
AID - iovs.14-13894 [pii]
AID - 10.1167/iovs.14-13894 [doi]
PST - epublish
SO  - Invest Ophthalmol Vis Sci. 2014 Oct 14;55(11):7410-6. doi: 10.1167/iovs.14-13894.