PMID- 25317176
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20141015
LR  - 20231110
IS  - 1687-9627 (Print)
IS  - 1687-9635 (Electronic)
VI  - 2014
DP  - 2014
TI  - Spontaneous massive splenic infarction in the setting of renal transplant and 
      septic shock: a case report and review of the literature.
PG  - 510259
LID - 10.1155/2014/510259 [doi]
LID - 510259
AB  - Massive splenic infarction (MSI) is a rare phenomenon that results from 
      compromised blood flow to more than half of the spleen. Causes of MSI include 
      hematological disorders, coagulopathies, infection, and embolization, and, 
      rarely, MSI is spontaneous. The mainstay of treatment is splenectomy. We report 
      the case of a 50-year-old man with a history of renal transplant who presented 
      with diffuse abdominal pain and rapidly developed septic shock. A computed 
      tomographic study (CT scan) of the abdomen demonstrated MSI. The surgical team 
      was consulted for splenectomy but conservative management was maintained and 
      immune function preserved. The patient's clinical condition was resolved over a 
      three-week period. This report demonstrates successful nonoperative management of 
      a spontaneous MSI most likely secondary to hypoperfusion and a hypercoagulable 
      state from both septic shock and renal transplant.
FAU - Bokman, Christine L
AU  - Bokman CL
AD  - DeWitt-Daughtry Family, Department of Surgery, University of Miami Miller School 
      of Medicine and Ryder Trauma Center/Jackson Memorial Hospital, Miami, FL 33136, 
      USA.
FAU - Sfeir, Maroun
AU  - Sfeir M
AD  - Department of Internal Medicine, University of Miami Miller School of Medicine 
      and Jackson Memorial Hospital, Miami, FL 33136, USA.
FAU - Chahwala, Veer
AU  - Chahwala V
AUID- ORCID: 0000-0003-1468-0126
AD  - DeWitt-Daughtry Family, Department of Surgery, University of Miami Miller School 
      of Medicine and Ryder Trauma Center/Jackson Memorial Hospital, Miami, FL 33136, 
      USA.
FAU - Ginzburg, Enrique
AU  - Ginzburg E
AD  - DeWitt-Daughtry Family, Department of Surgery, University of Miami Miller School 
      of Medicine and Ryder Trauma Center/Jackson Memorial Hospital, Miami, FL 33136, 
      USA.
LA  - eng
PT  - Journal Article
DEP - 20140915
PL  - United States
TA  - Case Rep Med
JT  - Case reports in medicine
JID - 101512910
PMC - PMC4181790
EDAT- 2014/10/16 06:00
MHDA- 2014/10/16 06:01
PMCR- 2014/09/15
CRDT- 2014/10/16 06:00
PHST- 2014/07/03 00:00 [received]
PHST- 2014/09/05 00:00 [revised]
PHST- 2014/09/08 00:00 [accepted]
PHST- 2014/10/16 06:00 [entrez]
PHST- 2014/10/16 06:00 [pubmed]
PHST- 2014/10/16 06:01 [medline]
PHST- 2014/09/15 00:00 [pmc-release]
AID - 10.1155/2014/510259 [doi]
PST - ppublish
SO  - Case Rep Med. 2014;2014:510259. doi: 10.1155/2014/510259. Epub 2014 Sep 15.