PMID- 25322841
OWN - NLM
STAT- MEDLINE
DCOM- 20160329
LR  - 20190221
IS  - 1423-0216 (Electronic)
IS  - 1021-7401 (Linking)
VI  - 22
IP  - 4
DP  - 2015
TI  - The association of openness personality trait with stress-related salivary 
      biomarkers in burning mouth syndrome.
PG  - 250-5
LID - 10.1159/000367714 [doi]
AB  - BACKGROUND: Burning mouth syndrome (BMS) is a chronic disorder defined as a 
      burning sensation in the oral mucosa without evidence of pathological findings. 
      Its pathophysiology is largely unknown, but psychiatric disorders and personality 
      traits have been implicated. OBJECTIVE: This study investigated whether there is 
      any association between salivary biomarkers and personality traits in BMS 
      patients. METHODS: It was a cross-sectional, controlled study that evaluated 30 
      individuals with BMS and 32 controls. All subjects were assessed with a 
      structured psychiatric interview (Mini International Neuropsychiatric Interview) 
      and the Big Five inventory. Salivary levels of brain-derived neurotrophic factor 
      (BDNF), neural growth factor, tumor necrosis factor-alpha, interleukin (IL)-6, IL-10 
      and cortisol were determined. RESULTS: We found that BMS patients exhibited more 
      traits of neuroticism and lower openness than controls. Openness showed a 
      moderate and negative correlation with cortisol, BDNF and IL-6. CONCLUSION: 
      Personality traits are associated with salivary biomarkers in BMS.
CI  - (c) 2014 S. Karger AG, Basel.
FAU - de Souza, Fabricio T A
AU  - de Souza FT
AD  - Department of Oral Pathology and Surgery, School of Dentistry, Universidade 
      Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.
FAU - Kummer, Arthur
AU  - Kummer A
FAU - Silva, Maiza L V
AU  - Silva ML
FAU - Amaral, Tania M P
AU  - Amaral TM
FAU - Abdo, Evandro N
AU  - Abdo EN
FAU - Abreu, Mauro H N G
AU  - Abreu MH
FAU - Silva, Tarcilia A
AU  - Silva TA
FAU - Teixeira, Antonio L
AU  - Teixeira AL
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20141015
PL  - Switzerland
TA  - Neuroimmunomodulation
JT  - Neuroimmunomodulation
JID - 9422763
RN  - 0 (Biomarkers)
RN  - 0 (Brain-Derived Neurotrophic Factor)
RN  - 0 (IL10 protein, human)
RN  - 0 (IL6 protein, human)
RN  - 0 (Interleukin-6)
RN  - 0 (TNF protein, human)
RN  - 0 (Tumor Necrosis Factor-alpha)
RN  - 130068-27-8 (Interleukin-10)
RN  - 7171WSG8A2 (BDNF protein, human)
RN  - 9061-61-4 (Nerve Growth Factor)
RN  - WI4X0X7BPJ (Hydrocortisone)
SB  - IM
MH  - Aged
MH  - Anxiety Disorders/*physiopathology
MH  - Biomarkers/metabolism
MH  - Brain-Derived Neurotrophic Factor/metabolism
MH  - Burning Mouth Syndrome/*metabolism/physiopathology
MH  - Cross-Sectional Studies
MH  - Female
MH  - Humans
MH  - Hydrocortisone/metabolism
MH  - Interleukin-10/metabolism
MH  - Interleukin-6/metabolism
MH  - Male
MH  - Middle Aged
MH  - Nerve Growth Factor/metabolism
MH  - Neuroticism
MH  - Personality/*physiology
MH  - Saliva/chemistry
MH  - Stress, Psychological/*metabolism/physiopathology
MH  - Tumor Necrosis Factor-alpha/metabolism
EDAT- 2014/10/18 06:00
MHDA- 2016/03/30 06:00
CRDT- 2014/10/18 06:00
PHST- 2014/06/19 00:00 [received]
PHST- 2014/08/20 00:00 [accepted]
PHST- 2014/10/18 06:00 [entrez]
PHST- 2014/10/18 06:00 [pubmed]
PHST- 2016/03/30 06:00 [medline]
AID - 000367714 [pii]
AID - 10.1159/000367714 [doi]
PST - ppublish
SO  - Neuroimmunomodulation. 2015;22(4):250-5. doi: 10.1159/000367714. Epub 2014 Oct 
      15.