PMID- 25323569
OWN - NLM
STAT- MEDLINE
DCOM- 20150518
LR  - 20181202
IS  - 1552-8618 (Electronic)
IS  - 0730-7268 (Linking)
VI  - 34
IP  - 1
DP  - 2015 Jan
TI  - Modeling PCB transfer into hen eggs: influence of physiological characteristics 
      of the animal.
PG  - 173-83
LID - 10.1002/etc.2781 [doi]
AB  - Laying hens are likely to be exposed to a wide range of persistent organic 
      pollutants (POPs), including polychlorinated biphenyls (PCBs). To improve the 
      safety of poultry farming systems in terms of POPs, the present research focused 
      on assessing the impact of physiological characteristics of the hen on the 
      transfer of ingested PCBs to eggs. Modeling was used as a research tool to 
      explore the impact of some physiological characteristics on the transfer of PCBs 
      in the laying hen. The mathematical model simulates the dynamics of the size of 
      the lipid compartments in the animal and the frequency of laying, with the PCB 
      concentrations in egg yolk and adipose tissue being model outputs. Simulations 
      were run to assess effects of animal characteristics on the transfer of PCBs to 
      eggs. Laying rate proportionally influenced the PCB level of eggs and adipose 
      tissue at steady state. Body fat diluted absorbed PCBs in the absence of laying 
      and significantly influenced the decontamination rate of tissues during 
      depuration after an exposure period. Application of the present model to actual 
      exposure cases highlights its value in improving the support of risk management 
      in livestock farming.
CI  - (c) 2014 SETAC.
FAU - Fournier, Agnes
AU  - Fournier A
AD  - Universite de Lorraine, ENSAIA, UR Animal et Fonctionnalites des Produits 
      Animaux, Vandoeuvre-les-Nancy, France; INRA, USC 340 Animal et Fonctionnalites 
      des Produits Animaux, Vandoeuvre-les-Nancy, France.
FAU - Martin, Olivier
AU  - Martin O
FAU - Travel, Angelique
AU  - Travel A
FAU - Puillet, Laurence
AU  - Puillet L
FAU - Feidt, Cyril
AU  - Feidt C
FAU - Jondreville, Catherine
AU  - Jondreville C
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20141125
PL  - United States
TA  - Environ Toxicol Chem
JT  - Environmental toxicology and chemistry
JID - 8308958
RN  - 0 (Environmental Pollutants)
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
SB  - IM
MH  - Animals
MH  - Chickens/*physiology
MH  - Egg Yolk/chemistry
MH  - Environmental Pollutants/*analysis
MH  - Female
MH  - Ovum/*chemistry
MH  - Polychlorinated Biphenyls/*analysis
OTO - NOTNLM
OT  - Kinetics
OT  - Model
OT  - Molt
OT  - Persistent organic pollutants
OT  - Poultry
EDAT- 2014/10/18 06:00
MHDA- 2015/05/20 06:00
CRDT- 2014/10/18 06:00
PHST- 2014/08/02 00:00 [received]
PHST- 2014/09/15 00:00 [revised]
PHST- 2014/10/10 00:00 [accepted]
PHST- 2014/10/18 06:00 [entrez]
PHST- 2014/10/18 06:00 [pubmed]
PHST- 2015/05/20 06:00 [medline]
AID - 10.1002/etc.2781 [doi]
PST - ppublish
SO  - Environ Toxicol Chem. 2015 Jan;34(1):173-83. doi: 10.1002/etc.2781. Epub 2014 Nov 
      25.