PMID- 25323920
OWN - NLM
STAT- MEDLINE
DCOM- 20150723
LR  - 20141118
IS  - 1423-0267 (Electronic)
IS  - 0030-3755 (Linking)
VI  - 232
IP  - 3
DP  - 2014
TI  - Evaluating dissociated optic nerve fiber layer appearance using en face layer 
      imaging produced by optical coherence tomography.
PG  - 170-8
LID - 10.1159/000364811 [doi]
AB  - PURPOSE: To investigate the incidence of and risk factors for a dissociated optic 
      nerve fiber layer (DONFL) appearance after pars plana vitrectomy (PPV). METHODS: 
      We retrospectively reviewed 189 eyes that underwent PPV with internal limiting 
      membrane removal and judged the presence/absence of an apparent DONFL based on en 
      face layer images produced by spectral-domain optical coherence tomography 
      (SD-OCT). RESULTS: An apparent DONFL was observed in 47 (24.9%) eyes. The 
      incidence of an apparent DONFL was significantly higher in the macular hole (MH) 
      group (76.5%) than in the non-MH group (epiretinal membrane, diabetic macular 
      edema, retinal vein occlusion, and others; 4.9%; p < 0.001). In the logistic 
      regression analysis, surgical indication for MH was identified as the most 
      significant DONFL risk factor (odds ratio 63.7; p = 1.05 x 10(-8)). CONCLUSION: 
      Postoperative OCT en face layer imaging clarified that MH eyes are liable to have 
      an apparent DONFL following PPV.
CI  - 2014 S. Karger AG, Basel
FAU - Kusuhara, Sentaro
AU  - Kusuhara S
AD  - Division of Ophthalmology, Department of Surgery, Kobe University Graduate School 
      of Medicine, Kobe, Japan.
FAU - Matsumiya, Wataru
AU  - Matsumiya W
FAU - Imai, Hisaori
AU  - Imai H
FAU - Honda, Shigeru
AU  - Honda S
FAU - Tsukahara, Yasutomo
AU  - Tsukahara Y
FAU - Negi, Akira
AU  - Negi A
LA  - eng
PT  - Journal Article
DEP - 20141015
PL  - Switzerland
TA  - Ophthalmologica
JT  - Ophthalmologica. Journal international d'ophtalmologie. International journal of 
      ophthalmology. Zeitschrift fur Augenheilkunde
JID - 0054655
SB  - IM
MH  - Aged
MH  - Epiretinal Membrane/surgery
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Nerve Fibers/*pathology
MH  - Optic Disk/*pathology
MH  - Postoperative Period
MH  - Retinal Perforations/*diagnosis
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Tomography, Optical Coherence/*methods
MH  - Visual Acuity/physiology
MH  - Vitrectomy
EDAT- 2014/10/18 06:00
MHDA- 2015/07/24 06:00
CRDT- 2014/10/18 06:00
PHST- 2013/11/29 00:00 [received]
PHST- 2014/05/22 00:00 [accepted]
PHST- 2014/10/18 06:00 [entrez]
PHST- 2014/10/18 06:00 [pubmed]
PHST- 2015/07/24 06:00 [medline]
AID - 000364811 [pii]
AID - 10.1159/000364811 [doi]
PST - ppublish
SO  - Ophthalmologica. 2014;232(3):170-8. doi: 10.1159/000364811. Epub 2014 Oct 15.