PMID- 25325460
OWN - NLM
STAT- MEDLINE
DCOM- 20150924
LR  - 20211021
IS  - 1550-9109 (Electronic)
IS  - 0161-8105 (Print)
IS  - 0161-8105 (Linking)
VI  - 38
IP  - 3
DP  - 2015 Mar 1
TI  - Sleep apnea-related risk of motor vehicle accidents is reduced by continuous 
      positive airway pressure: Swedish Traffic Accident Registry data.
PG  - 341-9
LID - 10.5665/sleep.4486 [doi]
AB  - STUDY OBJECTIVES: Obstructive sleep apnea (OSA) is associated with an increased 
      risk of motor vehicle accidents (MVAs). The rate of MVAs in patients suspected of 
      having OSA was determined and the effect of continuous positive airway pressure 
      (CPAP) was investigated. DESIGN: MVA rate in patients referred for OSA was 
      compared to the rate in the general population using data from the Swedish 
      Traffic Accident Registry (STRADA), stratified for age and calendar year. The 
      risk factors for MVAs, using demographic and polygraphy data, and MVA rate before 
      and after CPAP were evaluated in the patient group. SETTING: Clinical sleep 
      laboratory and population based control (n = 635,786). PATIENTS: There were 1,478 
      patients, male sex 70.4%, mean age 53.6 (12.8) y. INTERVENTIONS: CPAP. 
      MEASUREMENTS AND RESULTS: The number of accidents (n = 74) among patients was 
      compared with the expected number (n = 30) from a control population (STRADA). An 
      increased MVA risk ratio of 2.45 was found among patients compared with controls 
      (P < 0.001). Estimated excess accident risk was most prominent in the elderly 
      patients (65-80 y, seven versus two MVAs). In patients, driving distance (km/y), 
      EDS (Epworth Sleepiness score >/= 16), short habitual sleep time (</=5 h/night), and 
      use of hypnotics were associated with increased MVA risk (odds ratios 1.2, 2.1, 
      2.7 and 2.1, all P </= 0.03). CPAP use >/= 4 h/night was associated with a reduction 
      of MVA incidence (7.6 to 2.5 accidents/1,000 drivers/y). CONCLUSIONS: The MVA 
      risk in this large cohort of unselected patients with OSA suggests a need for 
      accurate tools to identify individuals at risk. Sleep apnea severity (e.g., 
      apnea-hypopnea index) failed to identify patients at risk.
CI  - (c) 2015 Associated Professional Sleep Societies, LLC.
FAU - Karimi, Mahssa
AU  - Karimi M
AD  - Centre for Sleep and Vigilance Disorder, Sahlgrenska Academy, University of 
      Gothenburg, Gothenburg, Sweden.
FAU - Hedner, Jan
AU  - Hedner J
AD  - Centre for Sleep and Vigilance Disorder, Sahlgrenska Academy, University of 
      Gothenburg, Gothenburg, Sweden.
FAU - Habel, Henrike
AU  - Habel H
AD  - Department of Mathematical Sciences, Chalmers University of Technology and 
      Department of Mathematical Sciences University of Gothenburg, Gothenburg, Sweden.
FAU - Nerman, Olle
AU  - Nerman O
AD  - Department of Mathematical Sciences, Chalmers University of Technology and 
      Department of Mathematical Sciences University of Gothenburg, Gothenburg, Sweden.
FAU - Grote, Ludger
AU  - Grote L
AD  - Centre for Sleep and Vigilance Disorder, Sahlgrenska Academy, University of 
      Gothenburg, Gothenburg, Sweden.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150301
PL  - United States
TA  - Sleep
JT  - Sleep
JID - 7809084
SB  - IM
CIN - Sleep. 2015 Mar;38(3):331-2. PMID: 25669195
MH  - Accidents, Traffic/*prevention & control/psychology/*statistics & numerical data
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Automobile Driving/*psychology
MH  - Case-Control Studies
MH  - Cohort Studies
MH  - Continuous Positive Airway Pressure/*statistics & numerical data
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Motor Vehicles
MH  - Odds Ratio
MH  - Registries
MH  - Risk Factors
MH  - Sleep Apnea, Obstructive/psychology/*therapy
MH  - Sleep Stages/physiology
MH  - Sweden/epidemiology
MH  - Young Adult
PMC - PMC4335527
OTO - NOTNLM
OT  - CPAP
OT  - daytime sleepiness
OT  - driving distance
OT  - risk factors
OT  - traffic accident
EDAT- 2014/10/18 06:00
MHDA- 2015/09/25 06:00
PMCR- 2015/09/01
CRDT- 2014/10/18 06:00
PHST- 2014/02/18 00:00 [received]
PHST- 2014/09/14 00:00 [accepted]
PHST- 2014/10/18 06:00 [entrez]
PHST- 2014/10/18 06:00 [pubmed]
PHST- 2015/09/25 06:00 [medline]
PHST- 2015/09/01 00:00 [pmc-release]
AID - sp-00119-14 [pii]
AID - 10.5665/sleep.4486 [doi]
PST - epublish
SO  - Sleep. 2015 Mar 1;38(3):341-9. doi: 10.5665/sleep.4486.