PMID- 25326696
OWN - NLM
STAT- MEDLINE
DCOM- 20150625
LR  - 20211203
IS  - 1756-0500 (Electronic)
IS  - 1756-0500 (Linking)
VI  - 7
DP  - 2014 Oct 18
TI  - Primary pulmonary synovial sarcoma requiring differentiation from pulmonary 
      metastasis of tibial adamantinoma: a case report.
PG  - 736
LID - 10.1186/1756-0500-7-736 [doi]
LID - 736
AB  - BACKGROUND: Primary pulmonary synovial sarcoma (PPSS) is rare. We describe a case 
      of PPSS complicated by tibial adamantinoma that required differentiation from 
      lung metastasis. CASE PRESENTATION: A 39-year-old Japanese woman presented with 
      hemoptysis, dyspnea, and a well-defined tumor measuring 3.0 cm in greatest 
      diameter in the right lower lobe on chest computed tomography (CT). Positron 
      emission tomography/CT with fluorodeoxyglucose (FDG-PET/CT) showed mild uptake of 
      FDG (maximum standardized uptake value of 2.0). Her past history included surgery 
      for adamantinoma of the right tibia at age 25 years. We considered the 
      possibility of pulmonary metastasis from the adamantinoma and performed 
      fluoroscopy-assisted thoracoscopic resection of the tumor after CT-guided 
      Lipiodol marking. Histologically, the tumor was composed mainly of a dense 
      proliferation of spindle cells. Immunohistochemical studies were positive for 
      epithelial membrane antigen, B cell lymphoma 2, and transducing-like enhancer of 
      split 1. They were negative for CD34. The synovial sarcoma, X breakpoint 1 
      gene-fusion transcript was detected by reverse transcription-polymerase chain 
      reaction. It is diagnostic of PPSS. Resection margins were negative. The patient 
      was well without evidence of recurrence or metastasis of the PPSS or adamantinoma 
      at the 30-month and 15-year follow-ups. CONCLUSION: Clinical and radiological 
      manifestations of PPSS overlap with those of other lung tumors. The solitary 
      pulmonary nodule in this case was indistinguishable from pulmonary metastases of 
      the adamantinoma based on clinical symptoms, epidemiology, chest radiography, CT, 
      and FDG-PET/CT. PPSS was diagnosed only after evaluating gross pathology, 
      histology, immunohistochemistry, and cytogenetics. PPSS should be included in the 
      differential diagnosis of a well-defined homogeneous round or oval lung mass. To 
      our knowledge, this is the first report of PPSS complicated by adamantinoma.
FAU - Shirai, Toshiharu
AU  - Shirai T
AD  - Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural 
      University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan. 
      shi-ra-e@koto.kpu-m.ac.jp.
FAU - Tsuchida, Shinji
AU  - Tsuchida S
FAU - Terauchi, Ryu
AU  - Terauchi R
FAU - Mizoshiri, Naoki
AU  - Mizoshiri N
FAU - Konishi, Eiichi
AU  - Konishi E
FAU - Tomita, Yasuhiko
AU  - Tomita Y
FAU - Shimada, Junichi
AU  - Shimada J
FAU - Fujiwara, Hiroyoshi
AU  - Fujiwara H
FAU - Kubo, Toshikazu
AU  - Kubo T
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20141018
PL  - England
TA  - BMC Res Notes
JT  - BMC research notes
JID - 101462768
RN  - 0Z5B2CJX4D (Fluorodeoxyglucose F18)
SB  - IM
MH  - Adamantinoma/diagnostic imaging/*pathology/surgery
MH  - Adult
MH  - Diagnosis, Differential
MH  - Female
MH  - Fluorodeoxyglucose F18
MH  - Follow-Up Studies
MH  - Humans
MH  - Lung Neoplasms/diagnostic imaging/*secondary
MH  - Positron-Emission Tomography
MH  - Postoperative Care
MH  - Sarcoma, Synovial/*diagnosis/diagnostic imaging/*pathology
MH  - Tibia/diagnostic imaging/*pathology/surgery
MH  - Tomography, X-Ray Computed
PMC - PMC4210480
EDAT- 2014/10/20 06:00
MHDA- 2015/06/26 06:00
PMCR- 2014/10/18
CRDT- 2014/10/20 06:00
PHST- 2014/07/30 00:00 [received]
PHST- 2014/10/02 00:00 [accepted]
PHST- 2014/10/20 06:00 [entrez]
PHST- 2014/10/20 06:00 [pubmed]
PHST- 2015/06/26 06:00 [medline]
PHST- 2014/10/18 00:00 [pmc-release]
AID - 1756-0500-7-736 [pii]
AID - 3260 [pii]
AID - 10.1186/1756-0500-7-736 [doi]
PST - epublish
SO  - BMC Res Notes. 2014 Oct 18;7:736. doi: 10.1186/1756-0500-7-736.