PMID- 25329634
OWN - NLM
STAT- MEDLINE
DCOM- 20150629
LR  - 20141021
IS  - 1399-0039 (Electronic)
IS  - 0001-2815 (Linking)
VI  - 84
IP  - 5
DP  - 2014 Nov
TI  - Association between HLA-DR4 haplotypes and tuberculin skin test response in the 
      Ache population.
PG  - 479-83
LID - 10.1111/tan.12451 [doi]
AB  - The human leukocyte antigen (HLA) system has a major role in the regulation of 
      the immune response as it is involved in the defense against pathogens. Evidence 
      for association with tuberculosis (TB) is more consistent for class II than for 
      class I HLA genes. TB is important among indigenous peoples in South America, not 
      only because of its historical role in regional depopulation, but also because it 
      is still widespread. The aim of this study was to evaluate the association of HLA 
      class II alleles, haplotypes and genotypes and tuberculin skin test response 
      (TST) in 76 individuals of the Ache population. Poisson Regression was employed 
      to assess risk genotypes. DRB1*04, DQA1*03 and DQB1*03:02 were associated with 
      TST response in this population.
CI  - (c) 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
FAU - Lindenau, J D
AU  - Lindenau JD
AD  - Departamento de Genetica, Instituto de Biociencias, Universidade Federal do Rio 
      Grande do Sul, Porto Alegre, RS, Brazil.
FAU - Guimaraes, L S P
AU  - Guimaraes LS
FAU - Hurtado, A M
AU  - Hurtado AM
FAU - Hill, K R
AU  - Hill KR
FAU - Tsuneto, L T
AU  - Tsuneto LT
FAU - Salzano, F M
AU  - Salzano FM
FAU - Petzl-Erler, M L
AU  - Petzl-Erler ML
FAU - Hutz, M H
AU  - Hutz MH
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Tissue Antigens
JT  - Tissue antigens
JID - 0331072
RN  - 0 (HLA-DQ alpha-Chains)
RN  - 0 (HLA-DQ beta-Chains)
RN  - 0 (HLA-DQA1 antigen)
RN  - 0 (HLA-DQB1 antigen)
RN  - 0 (HLA-DR4 Antigen)
RN  - 0 (HLA-DRB1 Chains)
SB  - IM
MH  - *Alleles
MH  - Brazil
MH  - Female
MH  - HLA-DQ alpha-Chains/genetics
MH  - HLA-DQ beta-Chains/genetics
MH  - HLA-DR4 Antigen/*genetics
MH  - HLA-DRB1 Chains/genetics
MH  - *Haplotypes
MH  - Humans
MH  - *Indians, South American
MH  - Male
MH  - Tuberculin Test
MH  - Tuberculosis/*genetics
OTO - NOTNLM
OT  - Amerindians
OT  - anergy
OT  - human leukocyte antigen
OT  - tuberculin skin test response response
OT  - tuberculosis
EDAT- 2014/10/21 06:00
MHDA- 2015/06/30 06:00
CRDT- 2014/10/21 06:00
PHST- 2014/06/04 00:00 [received]
PHST- 2014/09/03 00:00 [revised]
PHST- 2014/09/12 00:00 [accepted]
PHST- 2014/10/21 06:00 [entrez]
PHST- 2014/10/21 06:00 [pubmed]
PHST- 2015/06/30 06:00 [medline]
AID - 10.1111/tan.12451 [doi]
PST - ppublish
SO  - Tissue Antigens. 2014 Nov;84(5):479-83. doi: 10.1111/tan.12451.