PMID- 25336022 OWN - NLM STAT- MEDLINE DCOM- 20150625 LR - 20211021 IS - 1471-2474 (Electronic) IS - 1471-2474 (Linking) VI - 15 DP - 2014 Oct 21 TI - In vivo microstructural analysis of the humeral greater tuberosity in patients with rotator cuff tears using multidetector row computed tomography. PG - 351 LID - 10.1186/1471-2474-15-351 [doi] LID - 351 AB - BACKGROUND: In arthroscopic surgery, the suture anchor technique has become popular for rotator cuff repair. Preoperative evaluation of the bone microstructure is of utmost importance because, especially in elderly patients, osteoporotic changes may cause anchor pullout, which results in failure of rotator cuff repair. Many groups have reported humeral microstructural analysis; however, most studies were experiments using porcine specimens or human cadavers. In this study, we used multidetector row computed tomography to successfully perform in vivo evaluation of the bone microstructure of the humeral greater tuberosity in patients with rotator cuff tears. METHODS: Ten patients were examined. Regions of interest were defined in six quadrants of the greater tuberosity (medial, lateral, and far lateral rows of the anterior and posterior areas). The local bone mineral density and the trabecular microstructural parameters, including the mean bone volume to total volume (BV/TV), trabecular thickness, trabecular separation, and structure model index (SMI), were measured using bone analysis software. RESULTS: The BV/TV of the posteromedial region was highest and the SMI of the posteromedial region was lowest. These findings suggest that the bone quality of the posteromedial portion is the highest within the greater tuberosity. CONCLUSION: Because the bone quality may be correlated with the pullout strength of suture anchors, our method can help to understand the individual and regional variance in bone quality and may lead to the creation of personalized surgical protocols. FAU - Sakamoto, Yoshihiro AU - Sakamoto Y AD - Department of Orthopaedic Surgery, Nara Medical University, 840 Shijocho, Kashihara, Nara 634-8521, Japan. sakayosi@naramed-u.ac.jp. FAU - Kido, Akira AU - Kido A FAU - Inoue, Kazuya AU - Inoue K FAU - Sakurai, Goro AU - Sakurai G FAU - Hashiuchi, Tomohisa AU - Hashiuchi T FAU - Munemoto, Mitsuru AU - Munemoto M FAU - Tanaka, Yasuhito AU - Tanaka Y LA - eng PT - Journal Article DEP - 20141021 PL - England TA - BMC Musculoskelet Disord JT - BMC musculoskeletal disorders JID - 100968565 SB - IM MH - Aged MH - Arthroscopy MH - Bone Density MH - Female MH - Humans MH - Humerus/*anatomy & histology/*diagnostic imaging/pathology/surgery MH - Imaging, Three-Dimensional MH - Male MH - Middle Aged MH - *Multidetector Computed Tomography MH - Osteoporosis/pathology MH - Rotator Cuff/*diagnostic imaging/surgery MH - *Rotator Cuff Injuries MH - Suture Anchors MH - Suture Techniques PMC - PMC4216346 EDAT- 2014/10/23 06:00 MHDA- 2015/06/26 06:00 PMCR- 2014/10/21 CRDT- 2014/10/23 06:00 PHST- 2014/05/27 00:00 [received] PHST- 2014/10/03 00:00 [accepted] PHST- 2014/10/23 06:00 [entrez] PHST- 2014/10/23 06:00 [pubmed] PHST- 2015/06/26 06:00 [medline] PHST- 2014/10/21 00:00 [pmc-release] AID - 1471-2474-15-351 [pii] AID - 2288 [pii] AID - 10.1186/1471-2474-15-351 [doi] PST - epublish SO - BMC Musculoskelet Disord. 2014 Oct 21;15:351. doi: 10.1186/1471-2474-15-351.