PMID- 25340716
OWN - NLM
STAT- MEDLINE
DCOM- 20150624
LR  - 20141024
IS  - 1464-522X (Electronic)
IS  - 0309-1902 (Linking)
VI  - 38
IP  - 8
DP  - 2014 Nov
TI  - Effect of a multi-lead PCA approach on modified moving average method for T-wave 
      alternans detection.
PG  - 396-401
LID - 10.3109/03091902.2014.960605 [doi]
AB  - T-wave alternans, a beat-to-beat re-polarization pattern variation phenomenon, 
      plays an important role in sudden cardiac death prediction. The proposed method 
      modifies the currently available Modified Moving Average Method (MMAM) by a 
      multi-lead principal component analysis (PCA) approach. Application of PCA will 
      concentrate the alternans effect, which is supposed to be distributed on multiple 
      leads in a single derived lead. MMAM is applied to the derived lead and alternans 
      magnitude is measured. Results are compared with MMAM, implemented by the authors 
      and by an open source tool, TWAnalyser. The TWA Physionet/CinC 2008 Challenge 
      Database is used for testing. Performances are measured in terms of root mean 
      square error (rmse) and correlation coefficients. The rmse is highest for 
      TWAnalyser results and lowest for the proposed method. While the correlation 
      coefficient is highest for the proposed method, 0.88, that for normal MMAM is 
      0.73 and for TWAnalyser is 0.75. The proposed multi-lead PCA approach provides 
      improved performance of current MMAM.
FAU - Deogire, Aruna
AU  - Deogire A
AD  - MET's Institute of Engineering , Nashik, Maharashtra , India and.
FAU - Hamde, Satish
AU  - Hamde S
LA  - eng
PT  - Journal Article
PL  - England
TA  - J Med Eng Technol
JT  - Journal of medical engineering & technology
JID - 7702125
SB  - IM
MH  - Databases, Factual
MH  - *Electrocardiography
MH  - Humans
MH  - *Principal Component Analysis
MH  - *Signal Processing, Computer-Assisted
OTO - NOTNLM
OT  - ECG
OT  - PCA
OT  - T-wave alternans
OT  - multi-lead
EDAT- 2014/10/24 06:00
MHDA- 2015/06/25 06:00
CRDT- 2014/10/24 06:00
PHST- 2014/10/24 06:00 [entrez]
PHST- 2014/10/24 06:00 [pubmed]
PHST- 2015/06/25 06:00 [medline]
AID - 10.3109/03091902.2014.960605 [doi]
PST - ppublish
SO  - J Med Eng Technol. 2014 Nov;38(8):396-401. doi: 10.3109/03091902.2014.960605.