PMID- 25343674
OWN - NLM
STAT- MEDLINE
DCOM- 20150625
LR  - 20151119
IS  - 1752-0371 (Electronic)
IS  - 1752-0363 (Linking)
VI  - 8
IP  - 8
DP  - 2014
TI  - High-sensitivity troponin: where are we now and where do we go from here?
PG  - 1021-32
LID - 10.2217/bmm.14.54 [doi]
AB  - High-sensitivity troponin (hsTn) assays are used clinically in most parts of the 
      world and are expected to be approved by the US FDA for clinical use in the USA 
      soon. Clinical use of hsTn leads to improvements in the detection of myocardial 
      injury, shorter time to ruling out acute myocardial infarction, improved 
      risk-stratification of patients with heart failure and atrial fibrillation among 
      others. HsTn may also guide strategies for primary and secondary prevention of 
      cardiovascular disease. However, unmet challenges remain, including 
      distinguishing between acute and chronic hsTn elevations, distinguishing between 
      type 1 and type 2 acute myocardial infarction and determining whether to use 
      gender-neutral or gender-specific reference values.
FAU - Korley, Frederick K
AU  - Korley FK
AD  - Department of Emergency Medicine, Johns Hopkins University School of Medicine, 
      Davis Building, Suite 3220, 5801 Smith Avenue, Baltimore, MD 21209, USA.
FAU - Jaffe, Allan S
AU  - Jaffe AS
LA  - eng
PT  - Journal Article
PT  - Review
PL  - England
TA  - Biomark Med
JT  - Biomarkers in medicine
JID - 101312535
RN  - 0 (Biomarkers)
RN  - 0 (Troponin)
SB  - IM
MH  - Biomarkers/*metabolism
MH  - Cardiovascular Diseases/*prevention & control
MH  - Humans
MH  - Myocardial Infarction/*diagnosis/*metabolism
MH  - Prognosis
MH  - Troponin/*metabolism
OTO - NOTNLM
OT  - acute coronary syndrome
OT  - cardiovascular disease prevention
OT  - high-sensitivity troponin
OT  - review
OT  - structural heart disease
OT  - troponin
EDAT- 2014/10/25 06:00
MHDA- 2015/06/26 06:00
CRDT- 2014/10/25 06:00
PHST- 2014/10/25 06:00 [entrez]
PHST- 2014/10/25 06:00 [pubmed]
PHST- 2015/06/26 06:00 [medline]
AID - 10.2217/bmm.14.54 [doi]
PST - ppublish
SO  - Biomark Med. 2014;8(8):1021-32. doi: 10.2217/bmm.14.54.