PMID- 2534411
OWN - NLM
STAT- MEDLINE
DCOM- 19900511
LR  - 20191029
IS  - 0952-1178 (Print)
IS  - 0952-1178 (Linking)
VI  - 7
IP  - 6
DP  - 1989 Dec
TI  - Evidence for a further stimulation of atrial natriuretic factor release by atrial 
      pacing in patients with mitral stenosis.
PG  - S242-3
AB  - To investigate the release of atrial natriuretic factor (ANF) in mitral stenosis 
      and the effect of an increased atrial contraction frequency on atrial distension 
      and ANF secretion, we studied 14 patients [New York Heart Association (NYHA) 
      grades II-III] in sinus rhythm, undergoing cardiac catheterization for mitral 
      stenosis. Echocardiographic tracings, repeat determinations of mean pulmonary 
      artery wedge pressure and blood samples from the pulmonary artery for ANF 
      measurements were taken at baseline, during atrial pacing (125 beats/min for 5 
      min) and 5 min after pacing. After pacing, ANF levels rose markedly with a 
      parallel increase in mean pulmonary artery wedge pressure and left atrial size. 
      These data indicate that atrial pacing is capable of further stimulating ANF 
      release, even in patients with elevated baseline ANF and left atrial pressure and 
      an increased left atrial dimension.
FAU - Malatino, L S
AU  - Malatino LS
AD  - Istituto di Clinica Medica Luigi Condorelli, Catania, Italy.
FAU - Stancanelli, B
AU  - Stancanelli B
FAU - Greco, G
AU  - Greco G
FAU - Polizzi, G
AU  - Polizzi G
FAU - Leonardi, C
AU  - Leonardi C
FAU - Russo, G
AU  - Russo G
FAU - Tamburino, C
AU  - Tamburino C
FAU - Greco, G
AU  - Greco G
FAU - Giuffrida, G
AU  - Giuffrida G
FAU - Tamburino, G
AU  - Tamburino G
LA  - eng
PT  - Journal Article
PL  - England
TA  - J Hypertens Suppl
JT  - Journal of hypertension. Supplement : official journal of the International 
      Society of Hypertension
JID - 8501422
RN  - 85637-73-6 (Atrial Natriuretic Factor)
SB  - IM
MH  - Adult
MH  - Atrial Natriuretic Factor/blood/*metabolism
MH  - Cardiac Catheterization
MH  - *Cardiac Pacing, Artificial
MH  - Echocardiography
MH  - Female
MH  - Heart Atria/physiopathology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Mitral Valve Stenosis/blood/*physiopathology
MH  - Pulmonary Wedge Pressure/physiology
MH  - Time Factors
EDAT- 1989/12/01 00:00
MHDA- 1989/12/01 00:01
CRDT- 1989/12/01 00:00
PHST- 1989/12/01 00:00 [pubmed]
PHST- 1989/12/01 00:01 [medline]
PHST- 1989/12/01 00:00 [entrez]
AID - 10.1097/00004872-198900076-00117 [doi]
PST - ppublish
SO  - J Hypertens Suppl. 1989 Dec;7(6):S242-3. doi: 10.1097/00004872-198900076-00117.