PMID- 25351216 OWN - NLM STAT- MEDLINE DCOM- 20150527 LR - 20181202 IS - 1002-0098 (Print) IS - 1002-0098 (Linking) VI - 49 IP - 8 DP - 2014 Aug TI - [Clinical features of oral lesions in patients with human immunodeficiency virus infection/acquired immunodeficiency syndrome in Guangxi autonomous region]. PG - 459-63 AB - OBJECTIVE: To investigate the features of oral lesions in patients with human immunodeficiency virus infection/acquired immunodeficiency syndrome (HIV/AIDS). METHODS: A total of 127 HIV-seropositive patients were interviewed for health information and examined for their HIV-related oral lesions according to the EC Clearing House Criteria on Oral Problems related to HIV-Infection (1992). The examinations were conducted by dental specialist and HIV specialist. The CD4 T cell count in peripheral blood of the patients was tested by flow cytometry. The patients were divided into HIV- infected group (42) and AIDS group (85) according to CDC Classification System for HIV- Infected Adults and Adolescents (revised in 1993). Chi-square test was used to test the relationship between systemic disease and oral lesions, and the difference of the prevalence of oral lesions between the two groups. RESULTS: Among the 127 patients, oral candidiasis (51/127), oral hairy leukoplakia (24/127) were common oral manifestation. There was no relationship between the oral manifestation and systemic disease (P = 0.397). The occurrence of oral lesions and oral candidiasis was significantly different between the two groups (chi(2) = 7.684, P = 0.006; chi(2) = 14.410, P < 0.001). The CD4 count was related to the prevalence of oral lesions (P = 0.006) and oral candidasis (P = 0.003). CONCLUSIONS: Most oral lesions appeared before the appearance of systemic disease. Oral candidiasis and oral hairy leukoplakia were the most common lesions.Oral lesions had no relationship with systemic disease but could be still an indicator for disease progress. FAU - Yong, Xiangzhi AU - Yong X AD - Department of Periodontics and Oral Medicine, College of Stomatology, GuangXi Medical University, Nanning 530021, China. FAU - Jiang, Lanlan AU - Jiang L AD - Department of Periodontics and Oral Medicine, College of Stomatology, GuangXi Medical University, Nanning 530021, China. FAU - Lu, Xiangchan AU - Lu X AD - Department of Periodontics and Oral Medicine, College of Stomatology, GuangXi Medical University, Nanning 530021, China. FAU - Liu, Wei AU - Liu W AD - Department of Periodontics and Oral Medicine, College of Stomatology, GuangXi Medical University, Nanning 530021, China. FAU - Wu, Nianning AU - Wu N AD - Department of Periodontics and Oral Medicine, College of Stomatology, GuangXi Medical University, Nanning 530021, China. FAU - Tao, Renchuan AU - Tao R AD - Department of Periodontics and Oral Medicine, College of Stomatology, GuangXi Medical University, Nanning 530021, China. Email: taorenchuan@gmail.com. LA - chi PT - Journal Article PL - China TA - Zhonghua Kou Qiang Yi Xue Za Zhi JT - Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology JID - 8711066 SB - IM MH - Acquired Immunodeficiency Syndrome/*complications MH - CD4 Lymphocyte Count MH - CD4-Positive T-Lymphocytes MH - Candidiasis, Oral/*epidemiology MH - China/epidemiology MH - HIV Infections MH - Humans MH - Leukoplakia, Hairy MH - Mouth Diseases/complications/*epidemiology MH - Prevalence EDAT- 2014/10/30 06:00 MHDA- 2015/05/28 06:00 CRDT- 2014/10/30 06:00 PHST- 2014/10/30 06:00 [entrez] PHST- 2014/10/30 06:00 [pubmed] PHST- 2015/05/28 06:00 [medline] PST - ppublish SO - Zhonghua Kou Qiang Yi Xue Za Zhi. 2014 Aug;49(8):459-63.