PMID- 25363805
OWN - NLM
STAT- MEDLINE
DCOM- 20150910
LR  - 20161125
IS  - 1540-8191 (Electronic)
IS  - 0886-0440 (Linking)
VI  - 30
IP  - 1
DP  - 2015 Jan
TI  - Transit-time flow measurement as a predictor of coronary bypass graft failure at 
      one year angiographic follow-up.
PG  - 47-52
LID - 10.1111/jocs.12471 [doi]
AB  - BACKGROUND: Transit-time flow measurement (TTFM) is a commonly used 
      intraoperative method for evaluation of coronary artery bypass graft (CABG) 
      anastomoses. This study was undertaken to determine whether TTFM can also be used 
      to predict graft patency at one year postsurgery. METHODS: Three hundred 
      forty-five CABG patients with intraoperative graft flow measurements and one year 
      angiographic follow-up were analyzed. Graft failure was defined as more than 50% 
      stenosis including the "string sign." Logistic regression analysis was used to 
      analyze the risk of graft failure after one year based on graft vessel type, 
      anastomatic configuration, and coronary artery size. RESULTS: Nine hundred 
      eighty-two coronary anastomoses were performed of which 12% had signs of graft 
      failure at one year angiographic follow-up. In internal mammary arteries (IMAs), 
      analysis showed a 4% decrease in graft failure odds for every 1 mL/min increase 
      in TTFM (OR = 0.96, CI = [0.93; 0.99], p = 0.005). ROC analysis showed good 
      discriminative ability for TTFM alone AUC = 69.5% in IMA grafts. For single-vein 
      grafts the decrease in graft failure odds was 2% for every 1 mL/min increase in 
      TTFM (OR = 0.98; CI = [0.97; 1.00], p = 0.059) and AUC of 59.9%. There were no 
      significant relationships between TTFM and graft failure in other graft types or 
      graft configurations. CONCLUSION: The TTFM method has good discriminative ability 
      for assessing the risk of graft failure in certain graft types within the first 
      year after CABG surgery and is a valuable instrument for intraoperative quality 
      assessment of bypass grafts.
CI  - (c) 2014 Wiley Periodicals, Inc.
FAU - Lehnert, Per
AU  - Lehnert P
AD  - Department of Cardiothoracic Surgery, Rigshospitalet, Copenhagen University 
      Hospital, Denmark.
FAU - Moller, Christian H
AU  - Moller CH
FAU - Damgaard, Sune
AU  - Damgaard S
FAU - Gerds, Thomas A
AU  - Gerds TA
FAU - Steinbruchel, Daniel A
AU  - Steinbruchel DA
LA  - eng
PT  - Journal Article
DEP - 20141103
PL  - United States
TA  - J Card Surg
JT  - Journal of cardiac surgery
JID - 8908809
SB  - IM
CIN - J Card Surg. 2015 Dec;30(12):896. PMID: 25900400
CIN - J Card Surg. 2015 Dec;30(12):896-7. PMID: 27163121
MH  - Aged
MH  - Anastomosis, Surgical
MH  - *Coronary Angiography
MH  - *Coronary Artery Bypass
MH  - Coronary Vessels/diagnostic imaging/pathology
MH  - Female
MH  - Follow-Up Studies
MH  - Graft Occlusion, Vascular/*diagnosis/physiopathology
MH  - Humans
MH  - Logistic Models
MH  - Male
MH  - Mammary Arteries/diagnostic imaging/pathology/physiopathology/transplantation
MH  - Monitoring, Intraoperative/*methods
MH  - Predictive Value of Tests
MH  - Pulse Wave Analysis/*methods
MH  - Time Factors
MH  - Treatment Failure
MH  - Vascular Patency
EDAT- 2014/11/05 06:00
MHDA- 2015/09/12 06:00
CRDT- 2014/11/04 06:00
PHST- 2014/11/04 06:00 [entrez]
PHST- 2014/11/05 06:00 [pubmed]
PHST- 2015/09/12 06:00 [medline]
AID - 10.1111/jocs.12471 [doi]
PST - ppublish
SO  - J Card Surg. 2015 Jan;30(1):47-52. doi: 10.1111/jocs.12471. Epub 2014 Nov 3.