PMID- 25365908
OWN - NLM
STAT- MEDLINE
DCOM- 20141230
LR  - 20181202
IS  - 0125-2208 (Print)
IS  - 0125-2208 (Linking)
VI  - 97 Suppl 9
DP  - 2014 Sep
TI  - Cefazolin-related fever in postoperative spine surgery: a case report.
PG  - S144-8
AB  - BACKGROUND: There have been few reports describing antibiotic related fever 
      especially in the beta-lactam class of antibiotics. The present report is a case 
      of postoperative immediate-onset cefazolin-related fever in a lumbar spine 
      surgery patient. CASE REPORT: A 58-year-old woman presented with progressive low 
      back pain and neurogenic claudication of both extremities for six months. 
      Magnetic resonance imagese (MRI) of the lumbar spine indicated central canal 
      stenosis with nerve root compression from L4 to S1. After decompressive 
      laminectomy, pedicular screw fixation, and posterolateral fusion were performed, 
      the patient experienced-postoperative fever without obvious evidence of 
      infection. The blood and tip of drain bacterial culture grew no organisms. After 
      propholactic cefazolin was discontinued in postoperative day 5, the fever began 
      to declined and returned to normal on postoperative day 9. CONCLUSION: 
      Postoperative drug fever that is caused by prophylactic cefazolin may be delayed 
      in diagnosis because drug fever is usually diagnosed by exclusion after the 
      elimination of other potential causes. The research authors would like to 
      encourage physicians to be aware of this entity. Prompt cause identification can 
      obviate unnecessary diagnostic procedures and inappropriate treatments.
FAU - Wilartratsami, Sirichai
AU  - Wilartratsami S
FAU - Jutasompakorn, Pinpilai
AU  - Jutasompakorn P
FAU - Luksanapruksa, Panya
AU  - Luksanapruksa P
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Thailand
TA  - J Med Assoc Thai
JT  - Journal of the Medical Association of Thailand = Chotmaihet thangphaet
JID - 7507216
RN  - 0 (Anti-Bacterial Agents)
RN  - IHS69L0Y4T (Cefazolin)
SB  - IM
MH  - Anti-Bacterial Agents/*adverse effects
MH  - Cefazolin/*adverse effects
MH  - Female
MH  - Fever/*chemically induced
MH  - Humans
MH  - Laminectomy
MH  - Lumbar Vertebrae/surgery
MH  - Middle Aged
MH  - Postoperative Complications
MH  - Spinal Fusion
EDAT- 2014/11/05 06:00
MHDA- 2014/12/31 06:00
CRDT- 2014/11/05 06:00
PHST- 2014/11/05 06:00 [entrez]
PHST- 2014/11/05 06:00 [pubmed]
PHST- 2014/12/31 06:00 [medline]
PST - ppublish
SO  - J Med Assoc Thai. 2014 Sep;97 Suppl 9:S144-8.