PMID- 25367364
OWN - NLM
STAT- MEDLINE
DCOM- 20150723
LR  - 20231112
IS  - 1542-474X (Electronic)
IS  - 1082-720X (Print)
IS  - 1082-720X (Linking)
VI  - 19
IP  - 6
DP  - 2014 Nov
TI  - Left ventricular hypertrophy: The relationship between the electrocardiogram and 
      cardiovascular magnetic resonance imaging.
PG  - 524-33
LID - 10.1111/anec.12223 [doi]
AB  - Conventional assessment of left ventricular hypertrophy (LVH) using the 
      electrocardiogram (ECG), for example, by the Sokolow-Lyon, Romhilt-Estes or 
      Cornell criteria, have relied on assessing changes in the amplitude and/or 
      duration of the QRS complex of the ECG to quantify LV mass. ECG measures of LV 
      mass have typically been validated by imaging with echocardiography or 
      cardiovascular magnetic resonance imaging (CMR). However, LVH can be the result 
      of diverse etiologies, and LVH is also characterized by pathological changes in 
      myocardial tissue characteristics on the genetic, molecular, cellular, and tissue 
      level beyond a pure increase in the number of otherwise normal cardiomyocytes. 
      For example, slowed conduction velocity through the myocardium, which can be due 
      to diffuse myocardial fibrosis, has been shown to be an important determinant of 
      conventional ECG LVH criteria regardless of LV mass. Myocardial tissue 
      characterization by CMR has emerged to not only quantify LV mass, but also detect 
      and quantify the extent and severity of focal or diffuse myocardial fibrosis, 
      edema, inflammation, myocarditis, fatty replacement, myocardial disarray, and 
      myocardial deposition of amyloid proteins (amyloidosis), glycolipids (Fabry 
      disease), or iron (siderosis). This can be undertaken using CMR techniques 
      including late gadolinium enhancement (LGE), T1 mapping, T2 mapping, T2* mapping, 
      extracellular volume fraction (ECV) mapping, fat/water-weighted imaging, and 
      diffusion tensor CMR. This review presents an overview of current and emerging 
      concepts regarding the diagnostic possibilities of both ECG and CMR for LVH in an 
      attempt to narrow gaps in our knowledge regarding the ECG diagnosis of LVH.
CI  - (c) 2014 Wiley Periodicals, Inc.
FAU - Bacharova, Ljuba
AU  - Bacharova L
AD  - International Laser Center, Bratislava, Slovak Republic; Institute of 
      Pathophysiology, Medical School, Comenius University, Bratislava, Slovak 
      Republic.
FAU - Ugander, Martin
AU  - Ugander M
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20141104
PL  - United States
TA  - Ann Noninvasive Electrocardiol
JT  - Annals of noninvasive electrocardiology : the official journal of the 
      International Society for Holter and Noninvasive Electrocardiology, Inc
JID - 9607443
SB  - IM
MH  - Electrocardiography/*methods
MH  - Heart Ventricles/pathology
MH  - Humans
MH  - Hypertrophy, Left Ventricular/*diagnosis/pathology
MH  - Magnetic Resonance Imaging/*methods
MH  - Reproducibility of Results
PMC - PMC6932615
OTO - NOTNLM
OT  - cardiac MRI
OT  - electrocardiography
OT  - noninvasive techniques
EDAT- 2014/11/05 06:00
MHDA- 2015/07/24 06:00
PMCR- 2014/11/04
CRDT- 2014/11/05 06:00
PHST- 2014/11/05 06:00 [entrez]
PHST- 2014/11/05 06:00 [pubmed]
PHST- 2015/07/24 06:00 [medline]
PHST- 2014/11/04 00:00 [pmc-release]
AID - ANEC12223 [pii]
AID - 10.1111/anec.12223 [doi]
PST - ppublish
SO  - Ann Noninvasive Electrocardiol. 2014 Nov;19(6):524-33. doi: 10.1111/anec.12223. 
      Epub 2014 Nov 4.