PMID- 25369228
OWN - NLM
STAT- MEDLINE
DCOM- 20170109
LR  - 20170110
IS  - 0024-6921 (Print)
IS  - 0024-6921 (Linking)
VI  - 166
IP  - 5
DP  - 2014 Sep-Oct
TI  - Clinical case of the month: a 22-year-old man with AIDS presenting with shortness 
      of breath and an oral lesion.
PG  - 224-30
AB  - Since the development of combination antiretroviral therapy (cART), the incidence 
      and mortality associated with Kaposi sarcoma (KS) have been reduced, although not 
      eliminated. Clinical presentations of KS range from simple skin involvement to 
      disseminated disease, including involvement of the oral cavity and viscera, which 
      portends a more ominous prognosis. Multiple case reports and data from clinical 
      trials indicate that administration of systemic corticosteroids may aggravate KS. 
      We present a case of disseminated KS following administration of prednisone for 
      presumed immune reconstitution inflammatory syndrome (IRIS) associated with 
      fungal pneumonia in an HIV-infected individual. The discussion that follows 
      outlines the pathophysiology and clinical presentations associated with KS and 
      existing data for the role of corticosteroids in promoting KS progression.
FAU - Englert, Daniel
AU  - Englert D
AD  - Chief Resident of the Louisiana State University Health Sciences Center Internal 
      Medicine Residency Program.
FAU - Seal, Paula
AU  - Seal P
AD  - Assistant Professor of Medicine at Louisiana State University Health Sciences 
      Center in New Orleans in the section of Infectious Diseases.
FAU - Parsons, Chris
AU  - Parsons C
AD  - Associate Professor of Medicine and Microbiology and Director of the HIV Cancer 
      Care Program at Louisiana State University Health Sciences Center in New Orleans.
FAU - Arbour, Adrienne
AU  - Arbour A
AD  - former Chief Resident of Louisiana State University Health Sciences Center in New 
      Orleans Internal Medicine Residency Program.
FAU - Roberts, Evans 3rd
AU  - Roberts E 3rd
AD  - Resident in the Tulane University Pathology and Laboratory Medicine Program.
FAU - Lopez, Fred A
AU  - Lopez FA
AD  - Richard Vial Professor and Vice Chair for Education in the Department of Medicine 
      at LSUHSC-New Orleans.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
DEP - 20141012
PL  - United States
TA  - J La State Med Soc
JT  - The Journal of the Louisiana State Medical Society : official organ of the 
      Louisiana State Medical Society
JID - 7505618
SB  - IM
MH  - *Acquired Immunodeficiency Syndrome/complications/drug 
      therapy/pathology/physiopathology
MH  - Adult
MH  - Humans
MH  - *Lung Diseases, Fungal/drug therapy/etiology/pathology/physiopathology
MH  - Male
MH  - *Mouth Neoplasms/drug therapy/pathology/physiopathology
MH  - *Pneumonia/drug therapy/etiology/pathology/physiopathology
MH  - *Sarcoma, Kaposi/drug therapy/pathology/physiopathology
EDAT- 2014/11/05 06:00
MHDA- 2017/01/10 06:00
CRDT- 2014/11/05 06:00
PHST- 2014/11/05 06:00 [entrez]
PHST- 2014/11/05 06:00 [pubmed]
PHST- 2017/01/10 06:00 [medline]
PST - ppublish
SO  - J La State Med Soc. 2014 Sep-Oct;166(5):224-30. Epub 2014 Oct 12.