PMID- 25371728
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20211021
IS  - 1792-0981 (Print)
IS  - 1792-1015 (Electronic)
IS  - 1792-0981 (Linking)
VI  - 8
IP  - 6
DP  - 2014 Dec
TI  - Association between cardiothoracic ratio, left ventricular size and systolic 
      function in patients undergoing computed tomography coronary angiography.
PG  - 1757-1763
AB  - The present study aimed to investigate the association between cardiothoracic 
      ratio (CTR) and left ventricular (LV) systolic function parameters in patients 
      with or without preserved LV ejection fraction (LVEF). A total of 203 subjects 
      suspected with coronary artery disease underwent chest radiography and dual 
      source computed tomography coronary angiography (DSCT-CA). The LV systolic 
      function parameters: LV end-diastolic volume index (LVEDVI), LV end-systolic 
      volume index (LVESVI), and LVEF were measured from the DSCT-CA. The association 
      between CTR and LV systolic function parameters was analyzed according to LVEF 
      value (<55%, depressed LVEF group; versus >/=55%, preserved LVEF group) and CTR 
      value (<0.5, normal range CTR group; versus >/=0.5, larger CTR group). The LVEDVI 
      and LVESVI were higher in the depressed LVEF group compared with the preserved 
      LVEF group (108.56+/-57.15 vs. 67.52+/-14.56 ml/m(2), P<0.001; and 64.07+/-37.81 vs. 
      20.23+/-7.23 ml/m(2), P<0.001, respectively) and lower in the normal range CTR 
      group compared with the larger CTR group (67.10+/-15.00 vs. 77.30+/-34.32 ml/m(2), 
      P=0.009 and 21.94+/-8.96 vs. 28.97+/-26.54 ml/m(2), P=0.017, respectively). 
      Significant correlations were found between CTR and LVEDVI, and LVESVI and LVEF 
      in the depressed LVEF group (r=0.66, P<0.001; r=0.65, P<0.001; and r=-0.46, 
      P=0.018, respectively). However, there was no significant association detected 
      between CTR and LV systolic function parameters in the other subgroups. The 
      LVEDVI and LVESVI showed an inverse correlation with the LVEF in each group. 
      Although the CTR was not a reliable indicator of LV size and systolic function in 
      patients with preserved LVEF, it was correlated with LV size and LVEF in patients 
      with depressed LVEF.
FAU - Zhu, Yinsu
AU  - Zhu Y
AD  - Department of Radiology, The First Affiliated Hospital of Nanjing Medical 
      University, Nanjing, Jiangsu 210029, P.R. China.
FAU - Xu, Hai
AU  - Xu H
AD  - Department of Radiology, The First Affiliated Hospital of Nanjing Medical 
      University, Nanjing, Jiangsu 210029, P.R. China.
FAU - Zhu, Xiaomei
AU  - Zhu X
AD  - Department of Radiology, The First Affiliated Hospital of Nanjing Medical 
      University, Nanjing, Jiangsu 210029, P.R. China.
FAU - Wei, Yongyue
AU  - Wei Y
AD  - Department of Biostatistics, School of Public Health, Nanjing Medical University, 
      Nanjing, Jiangsu 210029, P.R. China.
FAU - Yang, Guanyu
AU  - Yang G
AD  - Laboratory of Image Science and Technology, School of Computer Science and 
      Engineering, Southeast University, Nanjing, Jiangsu 210096, P.R. China.
FAU - Xu, Yi
AU  - Xu Y
AD  - Department of Radiology, The First Affiliated Hospital of Nanjing Medical 
      University, Nanjing, Jiangsu 210029, P.R. China.
FAU - Tang, Lijun
AU  - Tang L
AD  - Department of Radiology, The First Affiliated Hospital of Nanjing Medical 
      University, Nanjing, Jiangsu 210029, P.R. China.
LA  - eng
PT  - Journal Article
DEP - 20141013
PL  - Greece
TA  - Exp Ther Med
JT  - Experimental and therapeutic medicine
JID - 101531947
PMC - PMC4217771
OTO - NOTNLM
OT  - cardiothoracic ratio
OT  - chest radiography
OT  - dual source computed tomography
OT  - left ventricular systolic function
OT  - left ventricular volume index
EDAT- 2014/11/06 06:00
MHDA- 2014/11/06 06:01
PMCR- 2014/10/13
CRDT- 2014/11/06 06:00
PHST- 2014/03/05 00:00 [received]
PHST- 2014/09/04 00:00 [accepted]
PHST- 2014/11/06 06:00 [entrez]
PHST- 2014/11/06 06:00 [pubmed]
PHST- 2014/11/06 06:01 [medline]
PHST- 2014/10/13 00:00 [pmc-release]
AID - etm-08-06-1757 [pii]
AID - 10.3892/etm.2014.2016 [doi]
PST - ppublish
SO  - Exp Ther Med. 2014 Dec;8(6):1757-1763. doi: 10.3892/etm.2014.2016. Epub 2014 Oct 
      13.