PMID- 25371980
OWN - NLM
STAT- MEDLINE
DCOM- 20150115
LR  - 20220321
IS  - 1560-2281 (Electronic)
IS  - 1083-3668 (Linking)
VI  - 19
IP  - 11
DP  - 2014
TI  - Monitoring the reduced scattering coefficient of bone tissues on the trajectory 
      of pedicle screw placement using near-infrared spectroscopy.
PG  - 117002
LID - 10.1117/1.JBO.19.11.117002 [doi]
AB  - Pedicle screw (PS) fixation has been widely used for spine diseases. Scientists 
      and clinicians employ several approaches to navigate PS during operation. We have 
      demonstrated the feasibility of monitoring the reduced scattering coefficient 
      (mu's) on the trajectory of PS using near-infrared spectroscopy (NIRS). To perform 
      the in-vitro monitoring, an NIRS measurement system was introduced and the 
      reduced scattering coefficients of different sites in porcine pedicle were 
      accurately deduced from the spectrum. Moreover, the changes of the reduced 
      scattering coefficient along the different paths were studied. The results show 
      reduced scattering coefficients on different regions of bones can be 
      significantly distinguished. Furthermore, monitoring experiments along different 
      paths confirmed that a reduced scattering coefficient would change versus the 
      depth of puncture in pedicles. Thus, the proposed monitoring system based on NIRS 
      provides a potential for guiding PS during operation.
FAU - Liu, Yangyang
AU  - Liu Y
AD  - Nanjing University of Aeronautics and Astronautics, Department of Biomedical 
      Engineering, 29 Yudao Street, Nanjing 210016, China.
FAU - Wang, Yuyan
AU  - Wang Y
AD  - Nanjing University of Aeronautics and Astronautics, Department of Biomedical 
      Engineering, 29 Yudao Street, Nanjing 210016, China.
FAU - Qian, Zhiyu
AU  - Qian Z
AD  - Nanjing University of Aeronautics and Astronautics, Department of Biomedical 
      Engineering, 29 Yudao Street, Nanjing 210016, China.
FAU - Zhao, Jinzhe
AU  - Zhao J
AD  - Nanjing University of Aeronautics and Astronautics, Department of Biomedical 
      Engineering, 29 Yudao Street, Nanjing 210016, China.
FAU - Cao, Xinzhi
AU  - Cao X
AD  - Nanjing University of Aeronautics and Astronautics, Department of Biomedical 
      Engineering, 29 Yudao Street, Nanjing 210016, ChinabNanjing General Hospital, 305 
      Zhongshan East Road, Nanjing 210016, China.
FAU - Li, Weitao
AU  - Li W
AD  - Nanjing University of Aeronautics and Astronautics, Department of Biomedical 
      Engineering, 29 Yudao Street, Nanjing 210016, China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Biomed Opt
JT  - Journal of biomedical optics
JID - 9605853
SB  - IM
MH  - Animals
MH  - *Bone and Bones/chemistry/physiology/surgery
MH  - *Pedicle Screws
MH  - Scattering, Radiation
MH  - Spectroscopy, Near-Infrared/*methods
MH  - Swine
EDAT- 2014/11/06 06:00
MHDA- 2015/01/16 06:00
CRDT- 2014/11/06 06:00
PHST- 2014/06/16 00:00 [received]
PHST- 2014/09/29 00:00 [accepted]
PHST- 2014/11/06 06:00 [entrez]
PHST- 2014/11/06 06:00 [pubmed]
PHST- 2015/01/16 06:00 [medline]
AID - 1934597 [pii]
AID - 10.1117/1.JBO.19.11.117002 [doi]
PST - ppublish
SO  - J Biomed Opt. 2014;19(11):117002. doi: 10.1117/1.JBO.19.11.117002.