PMID- 25379295
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20141107
LR  - 20200930
IS  - 2090-6447 (Print)
IS  - 2090-6455 (Electronic)
VI  - 2014
DP  - 2014
TI  - Severe periodontal disease associated with long-term treatment with intravenous 
      immunoglobulin.
PG  - 860804
LID - 10.1155/2014/860804 [doi]
LID - 860804
AB  - Intravenous immunoglobulin (IVIG) is used in the treatment of neuropathy. This 
      case report presents, for the first time, a patient with severe periodontal 
      destruction after chronic therapy with IVIG. The patient reported having 
      extracted his maxillary anterior teeth himself due to high mobility. Clinical 
      examination and radiographic images show a generalized and severe periodontitis. 
      No significant alterations in genetic or microbiological features were observed. 
      The present case suggests that periodontal disease aggravation could be 
      considered a new adverse effect of IVIG therapy. Postulated mechanisms are immune 
      complexes formation, complement activation, and a direct effect in osteoclasts. 
      In conclusion, it is important that patients that will receive IVIG treatment 
      underwent dental evaluation.
FAU - Correa, Joice Dias
AU  - Correa JD
AD  - Department of Oral Surgery and Pathology, School of Dentistry, Federal University 
      of Minas Gerais, 31270-901 Belo Horizonte, MG, Brazil.
FAU - Rocha, Amanda Leal
AU  - Rocha AL
AD  - Special Service for Diagnosis and Treatment in Dentistry (SEDTO), Hospital and 
      Clinics, Federal University of Minas Gerais, 30130-100 Belo Horizonte, MG, 
      Brazil.
FAU - Costa, Lidiane Cristina Machado
AU  - Costa LC
AD  - Department of Oral Surgery and Pathology, School of Dentistry, Federal University 
      of Minas Gerais, 31270-901 Belo Horizonte, MG, Brazil.
FAU - Travassos, Denise
AU  - Travassos D
AD  - Special Service for Diagnosis and Treatment in Dentistry (SEDTO), Hospital and 
      Clinics, Federal University of Minas Gerais, 30130-100 Belo Horizonte, MG, Brazil 
      ; Department of Community and Preventive Dentistry, School of Dentistry, Federal 
      University of Minas Gerais, 31270-901 Belo Horizonte, MG, Brazil.
FAU - Castro, Wagner Henriques
AU  - Castro WH
AD  - Department of Oral Surgery and Pathology, School of Dentistry, Federal University 
      of Minas Gerais, 31270-901 Belo Horizonte, MG, Brazil ; Special Service for 
      Diagnosis and Treatment in Dentistry (SEDTO), Hospital and Clinics, Federal 
      University of Minas Gerais, 30130-100 Belo Horizonte, MG, Brazil.
FAU - Garlet, Gustavo Pompermaier
AU  - Garlet GP
AD  - Department of Biological Sciences, Bauru School of Dentistry, University of Sao 
      Paulo, 17012-901 Bauru, SP, Brazil.
FAU - Gomez, Rodrigo Santiago
AU  - Gomez RS
AD  - Neurology Service, Hospital and Clinics, Federal University of Minas Gerais, 
      30130-100 Belo Horizonte, MG, Brazil.
FAU - Teixeira, Antonio Lucio
AU  - Teixeira AL
AD  - Neurology Service, Hospital and Clinics, Federal University of Minas Gerais, 
      30130-100 Belo Horizonte, MG, Brazil.
FAU - Silva, Tarcilia Aparecida
AU  - Silva TA
AD  - Department of Oral Surgery and Pathology, School of Dentistry, Federal University 
      of Minas Gerais, 31270-901 Belo Horizonte, MG, Brazil ; Special Service for 
      Diagnosis and Treatment in Dentistry (SEDTO), Hospital and Clinics, Federal 
      University of Minas Gerais, 30130-100 Belo Horizonte, MG, Brazil.
LA  - eng
PT  - Journal Article
DEP - 20141015
PL  - Egypt
TA  - Case Rep Dent
JT  - Case reports in dentistry
JID - 101573242
PMC - PMC4213401
EDAT- 2014/11/08 06:00
MHDA- 2014/11/08 06:01
PMCR- 2014/10/15
CRDT- 2014/11/08 06:00
PHST- 2014/07/08 00:00 [received]
PHST- 2014/09/18 00:00 [accepted]
PHST- 2014/11/08 06:00 [entrez]
PHST- 2014/11/08 06:00 [pubmed]
PHST- 2014/11/08 06:01 [medline]
PHST- 2014/10/15 00:00 [pmc-release]
AID - 10.1155/2014/860804 [doi]
PST - ppublish
SO  - Case Rep Dent. 2014;2014:860804. doi: 10.1155/2014/860804. Epub 2014 Oct 15.