PMID- 25380871
OWN - NLM
STAT- MEDLINE
DCOM- 20151117
LR  - 20181202
IS  - 1873-2623 (Electronic)
IS  - 0041-1345 (Linking)
VI  - 46
IP  - 8
DP  - 2014 Oct
TI  - Evaluation of the prevalence of insertion element IS16 in vancomycin-resistant 
      enterococci strains of Enterococcus faecium isolated from transplantology 
      patients from a Warsaw Hospital between 2010 and 2012.
PG  - 2583-5
LID - S0041-1345(14)00777-5 [pii]
LID - 10.1016/j.transproceed.2014.08.025 [doi]
AB  - The study included 79 vancomycin-resistant Enterococcus faecium (VRE) strains 
      isolated from 33 patients after kidney (n = 19) or liver (n = 14) 
      transplantation; these patients were hospitalized between 2010 and 2012. The 
      strains were obtained from infected persons as well as from carriers. All 
      examined strains were tested for the susceptibility to antimicrobials active 
      against enterococci and for the presence of vanA and vanB genes as well as the 
      presence of the insertion sequence IS16 considered as one of the markers of 
      hospital-associated strains. All 79 VRE strains of E faecium possessed IS16 and 
      the vanA (vanB-negative) determinant. All tested strains were resistant to at 
      least three groups of drugs; therefore, they were recognized as multidrug 
      resistant. All isolates were resistant to glycopeptides, ampicillin, and most 
      were resistant to tetracyclines, macrolides, nitrofurans, and high concentrations 
      of aminoglycosides. The presence of insertion element IS16 and multiple 
      resistance determinants prove that strains colonizing or infecting solid organ 
      recipients were typical nosocomial pathogens.
FAU - Chabros, L
AU  - Chabros L
AD  - Department of Medical Microbiology, The Infant Jesus Teaching Hospital (IJTH) in 
      Warsaw, Warsaw, Poland.
FAU - Szymanek-Majchrzak, K
AU  - Szymanek-Majchrzak K
AD  - Department of Medical Microbiology, The Infant Jesus Teaching Hospital (IJTH) in 
      Warsaw, Warsaw, Poland.
FAU - Mlynarczyk, A
AU  - Mlynarczyk A
AD  - Department of Medical Microbiology, The Infant Jesus Teaching Hospital (IJTH) in 
      Warsaw, Warsaw, Poland; Department of Dental Microbiology, Medical University of 
      Warsaw, Warsaw, Poland.
FAU - Sawicka-Grzelak, A
AU  - Sawicka-Grzelak A
AD  - Department of Medical Microbiology, The Infant Jesus Teaching Hospital (IJTH) in 
      Warsaw, Warsaw, Poland.
FAU - Durlik, M
AU  - Durlik M
AD  - Department of Medical Microbiology, The Infant Jesus Teaching Hospital (IJTH) in 
      Warsaw, Warsaw, Poland; Department of Transplant Medicine and Nephrology, 
      Transplantology Institute, Medical University of Warsaw, Warsaw, Poland.
FAU - Paczek, L
AU  - Paczek L
AD  - Department of Medical Microbiology, The Infant Jesus Teaching Hospital (IJTH) in 
      Warsaw, Warsaw, Poland; Department of Immunology, Transplantology and Internal 
      Diseases, Transplantology Institute, Medical University of Warsaw, Warsaw, 
      Poland.
FAU - Chmura, A
AU  - Chmura A
AD  - Department of Medical Microbiology, The Infant Jesus Teaching Hospital (IJTH) in 
      Warsaw, Warsaw, Poland; Department of General and Transplantation Surgery, 
      Transplantology Institute, Medical University of Warsaw, Warsaw, Poland.
FAU - Mlynarczyk, G
AU  - Mlynarczyk G
AD  - Department of Medical Microbiology, The Infant Jesus Teaching Hospital (IJTH) in 
      Warsaw, Warsaw, Poland. Electronic address: grazyna.mlynarczyk@wum.edu.pl.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Transplant Proc
JT  - Transplantation proceedings
JID - 0243532
RN  - 0 (DNA Transposable Elements)
SB  - IM
MH  - Bacterial Typing Techniques/methods
MH  - Cross Infection
MH  - *DNA Transposable Elements
MH  - Drug Resistance, Multiple, Bacterial
MH  - Enterococcus faecium/drug effects/*genetics
MH  - Humans
MH  - Immunocompromised Host
MH  - Multilocus Sequence Typing
MH  - Poland
MH  - Prevalence
MH  - Transplant Recipients
MH  - Vancomycin-Resistant Enterococci/drug effects/*genetics
EDAT- 2014/11/09 06:00
MHDA- 2015/11/18 06:00
CRDT- 2014/11/09 06:00
PHST- 2014/11/09 06:00 [entrez]
PHST- 2014/11/09 06:00 [pubmed]
PHST- 2015/11/18 06:00 [medline]
AID - S0041-1345(14)00777-5 [pii]
AID - 10.1016/j.transproceed.2014.08.025 [doi]
PST - ppublish
SO  - Transplant Proc. 2014 Oct;46(8):2583-5. doi: 10.1016/j.transproceed.2014.08.025.