PMID- 25394436
OWN - NLM
STAT- MEDLINE
DCOM- 20150415
LR  - 20191113
IS  - 1319-2442 (Print)
IS  - 1319-2442 (Linking)
VI  - 25
IP  - 6
DP  - 2014 Nov
TI  - Do the outcomes of living donor renal allograft recipients differ with peritoneal 
      dialysis and hemodialysis as a bridge renal replacement therapy?
PG  - 1202-9
AB  - This study was undertaken to compare the outcomes of living donor renal 
      transplant recipients using peritoneal dialysis (PD) and hemodialysis (HD) as a 
      bridge modality for renal replacement therapy till renal transplantation. The 
      demographic profiles of the recipients and donors, the patients' native kidney 
      disease (diabetic versus non-diabetic), duration on dialysis, requirement of 
      anti-hypertensive drugs, number of blood transfusions, human leukocyte antigen 
      (HLA) mismatch status, pre- and post-transplant infectious complications, and 
      post-transplant outcomes of patients were compared between the two groups. The 
      demographic features of the study patients were similar in the two groups. The 
      duration of dialysis prior to transplant was significantly longer in the PD group 
      than in the HD group of patients. The anti-hypertensive drug requirement was 
      lower and the hemoglobin level and residual urine volume at the time of 
      transplant were relatively better in the PD patients compared to the HD patients. 
      The number of acute rejection episodes, delayed graft function, surgical 
      complications, glomerular filtration rate at one month and at the last follow-up, 
      were also similar in both groups. The short-term and long-term graft survival was 
      similar in both groups of patients. The one-, two-, five-, and eight-year 
      death-censored graft survival rates of the PD patients were 98, 95, 85, and 73%, 
      respectively, and in the HD group of patients, they were 100, 93, 84, and 79%, 
      respectively. The one-, two-, five-, and eight-year patient survival rates in the 
      PD group were 97, 92, 77, and 66%, respectively, and in the HD group, they were 
      97, 92, 79, and 69%, respectively. Our study suggests that the outcomes of the 
      living donor renal allograft recipients did not differ between the groups of 
      patients who used PD or HD as renal replacement therapy prior to renal 
      transplantation.
FAU - Prasad, Narayan
AU  - Prasad N
AD  - Department of Nephrology and Renal Transplantation, Sanjay Gandhi Postgraduate 
      Institute of Medical Sciences, Lucknow, India.
FAU - Vardhan, Harsh
AU  - Vardhan H
FAU - Baburaj, Vinod P
AU  - Baburaj VP
FAU - Bhadauria, Dharmendra
AU  - Bhadauria D
FAU - Gupta, Amit
AU  - Gupta A
FAU - Sharma, Raj K
AU  - Sharma RK
FAU - Kaul, Anupama
AU  - Kaul A
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Observational Study
PL  - Saudi Arabia
TA  - Saudi J Kidney Dis Transpl
JT  - Saudi journal of kidney diseases and transplantation : an official publication of 
      the Saudi Center for Organ Transplantation, Saudi Arabia
JID - 9436968
SB  - IM
MH  - Acute Disease
MH  - Adult
MH  - Allografts
MH  - Delayed Graft Function/etiology
MH  - Female
MH  - Graft Rejection/etiology
MH  - Graft Survival
MH  - Humans
MH  - Kaplan-Meier Estimate
MH  - Kidney Failure, Chronic/diagnosis/mortality/physiopathology/*therapy
MH  - Kidney Transplantation/adverse effects/*methods/mortality
MH  - *Living Donors
MH  - Male
MH  - Middle Aged
MH  - *Peritoneal Dialysis/adverse effects/mortality
MH  - *Renal Dialysis/adverse effects/mortality
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Time Factors
MH  - Treatment Outcome
MH  - Young Adult
EDAT- 2014/11/15 06:00
MHDA- 2015/04/16 06:00
CRDT- 2014/11/15 06:00
PHST- 2014/11/15 06:00 [entrez]
PHST- 2014/11/15 06:00 [pubmed]
PHST- 2015/04/16 06:00 [medline]
AID - SaudiJKidneyDisTranspl_2014_25_6_1202_144253 [pii]
AID - 10.4103/1319-2442.144253 [doi]
PST - ppublish
SO  - Saudi J Kidney Dis Transpl. 2014 Nov;25(6):1202-9. doi: 10.4103/1319-2442.144253.