PMID- 25402738
OWN - NLM
STAT- MEDLINE
DCOM- 20151001
LR  - 20171116
IS  - 1557-8518 (Electronic)
IS  - 1540-4196 (Linking)
VI  - 13
IP  - 1
DP  - 2015 Feb
TI  - Type 2 diabetes mellitus, metabolic syndrome, and mixed dyslipidemia: how 
      similar, how different, and how to treat?
PG  - 1-21
LID - 10.1089/met.2014.0049 [doi]
AB  - Individuals with mixed atherogenic dyslipidemia, type 2 diabetes mellitus (T2DM), 
      and metabolic syndrome are at high risk of developing cardiovascular disease 
      (CVD) and can often benefit greatly from preventive lifestyle and medical 
      interventions. These conditions typically co-exist in an individual, and the 
      lipid profiles associated with them have several features in common. The 
      worldwide prevalence of T2DM, atherogenic dyslipidemia, and metabolic syndrome is 
      increasing, particularly in southern Asia and the Middle East. Statins can lower 
      low-density lipoprotein-cholesterol and reduce the risk of CVD in these high-risk 
      individuals, but there is a residual risk of CVD associated with additional lipid 
      abnormalities, such as high levels of triglycerides and low levels of 
      high-density lipoprotein cholesterol. These abnormalities are commonly found in 
      patients with T2DM and metabolic syndrome. Additional lipid-modifying therapies 
      that target these abnormalities, such as fibrates and omega-3 polyunsaturated 
      fatty acids, may be able to improve lipid profiles and further reduce the risk of 
      CVD in these patients.
FAU - Halcox, Julian
AU  - Halcox J
AD  - 1 University of Swansea , Singleton Park, Swansea, United Kingdom .
FAU - Misra, Anoop
AU  - Misra A
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20141117
PL  - United States
TA  - Metab Syndr Relat Disord
JT  - Metabolic syndrome and related disorders
JID - 101150318
SB  - IM
MH  - Atherosclerosis/complications/diagnosis/epidemiology/therapy
MH  - Diabetes Mellitus, Type 2/complications/*diagnosis/epidemiology/*therapy
MH  - Dyslipidemias/complications/*diagnosis/epidemiology/*therapy
MH  - Humans
MH  - Metabolic Syndrome/complications/*diagnosis/epidemiology/*therapy
MH  - Practice Guidelines as Topic
EDAT- 2014/11/18 06:00
MHDA- 2015/10/02 06:00
CRDT- 2014/11/18 06:00
PHST- 2014/11/18 06:00 [entrez]
PHST- 2014/11/18 06:00 [pubmed]
PHST- 2015/10/02 06:00 [medline]
AID - 10.1089/met.2014.0049 [doi]
PST - ppublish
SO  - Metab Syndr Relat Disord. 2015 Feb;13(1):1-21. doi: 10.1089/met.2014.0049. Epub 
      2014 Nov 17.