PMID- 25409324 OWN - NLM STAT- MEDLINE DCOM- 20160622 LR - 20150105 IS - 1715-5320 (Electronic) IS - 1715-5312 (Linking) VI - 40 IP - 1 DP - 2015 Jan TI - The influence of nighttime feeding of carbohydrate or protein combined with exercise training on appetite and cardiometabolic risk in young obese women. PG - 37-45 LID - 10.1139/apnm-2014-0256 [doi] AB - Single macronutrient intake prior to sleep reduces appetite but may negatively impact insulin sensitivity in sedentary obese women. The present study examined the additive impact of nighttime feeding of whey (WH), casein (CAS), or carbohydrate (CHO) combined with exercise training on appetite, cardiometabolic health, and strength in obese women. Thirty-seven sedentary obese women (WH, n = 13, body mass index (BMI) 34.4 +/- 1.3 kg/m(2); CAS, n = 14, BMI 36.5 +/- 1.8 kg/m(2); CHO, n = 10, BMI 33.1 +/- 1.7 kg/m(2)) consumed WH, CAS, or CHO (140-150 kcal/serving), every night of the week, within 30 min of sleep, for 4 weeks. Supervised exercise training (2 days of resistance training and 1 day of high-intensity interval training) was completed 3 days per week. Pre- and post-testing measurements included appetite ratings, mood state, resting metabolic rate, fasting lipids, glucose, and hormonal responses (insulin, leptin, adiponectin, hs-CRP, IGF-1, and cortisol), body composition, and strength. Nighttime intake of CAS significantly (p < 0.05) increased morning satiety (pretraining, 25 +/- 5; post-training 41 +/- 6) more than WH (pretraining, 34 +/- 5; post-training, 35 +/- 6) or CHO (pre 40 +/- 8, post 43 +/- 7). Exercise training increased lean mass and strength, decreased body fat, and improved mood state in all groups. No other differences were noted. Nighttime feeding of CAS combined with exercise training increased morning satiety more than WH or CHO. Nighttime feeding for 4 weeks did not impact insulin sensitivity (assessed via homeostatic model assessment of insulin resistance) when combined with exercise training in obese women. ClinicalTrial.gov: NCT01830946. FAU - Ormsbee, Michael J AU - Ormsbee MJ AD - a Department of Nutrition, Food and Exercise Sciences, Florida State University, Tallahassee, FL 32306, USA. FAU - Kinsey, Amber W AU - Kinsey AW FAU - Eddy, Wyatt R AU - Eddy WR FAU - Madzima, Takudzwa A AU - Madzima TA FAU - Arciero, Paul J AU - Arciero PJ FAU - Figueroa, Arturo AU - Figueroa A FAU - Panton, Lynn B AU - Panton LB LA - eng SI - ClinicalTrials.gov/NCT01830946 PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't PL - Canada TA - Appl Physiol Nutr Metab JT - Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme JID - 101264333 RN - 0 (Appetite Depressants) RN - 0 (Biomarkers) RN - 0 (Caseins) RN - 0 (Dietary Carbohydrates) RN - 0 (Whey Proteins) SB - IM EIN - Appl Physiol Nutr Metab. 2019 Feb;44(2):228. PMID: 30652917 MH - Adult MH - Animals MH - Appetite Depressants/*therapeutic use MH - Appetite Regulation MH - Beverages MH - Biomarkers/blood MH - Body Mass Index MH - Caseins/*therapeutic use MH - Circadian Rhythm MH - Combined Modality Therapy MH - Dietary Carbohydrates/administration & dosage MH - Dietary Supplements MH - Double-Blind Method MH - *Exercise MH - *Feeding Behavior MH - Female MH - Humans MH - Insulin Resistance MH - *Muscle Strength MH - Obesity/blood/*diet therapy/metabolism/therapy MH - Patient Compliance MH - Whey Proteins/*therapeutic use OTO - NOTNLM OT - alimentation chronobiologique OT - chronobiological eating OT - entrainement par intervalle d'intensite elevee OT - exercice contre resistance OT - high intensity interval training OT - hormones OT - nutrition OT - resistance exercise EDAT- 2014/11/20 06:00 MHDA- 2016/06/23 06:00 CRDT- 2014/11/20 06:00 PHST- 2014/11/20 06:00 [entrez] PHST- 2014/11/20 06:00 [pubmed] PHST- 2016/06/23 06:00 [medline] AID - 10.1139/apnm-2014-0256 [doi] PST - ppublish SO - Appl Physiol Nutr Metab. 2015 Jan;40(1):37-45. doi: 10.1139/apnm-2014-0256.