PMID- 25411555
OWN - NLM
STAT- Publisher
LR  - 20191120
IS  - 1469-493X (Electronic)
IS  - 1361-6137 (Linking)
IP  - 2
DP  - 2000
TI  - Beta-blockers for heart failure.
LID - CD002131 [pii]
AB  - This is the protocol for a review and there is no abstract. The objectives are as 
      follows: Our objective is to appraise the effectiveness of beta blockers in 
      patients with heart failure. Our protocol defined main outcome is all cause 
      mortality. The specific a priori defined aims are to examine: the effectiveness 
      of beta blockers in all trials of patients with heart failure, and examine the 
      importance of the presence or absence of ischaemic cardiomyopathy in patients 
      included in trials and vasodilator properties of beta blocking agents used. We 
      will also examine the predictive value of left ventricular function, age, use of 
      angiotensin converting enzyme inhibitors and New York Heart Association Class 
      (NYHA), and the rate of discontinuation of therapy due to treatment. There are a 
      number of important ongoing trials for which data will become available in the 
      next few years. Thus a systematic review which may be updated regularly is 
      required to provide an up to date synthesis of the available data in this 
      increasingly important area.
FAU - Cleland, John Gf
AU  - Cleland JG
AD  - Academic Unit of Cardiology, Castle Hill Hospital, East Yorkshire, UK.
FAU - Freemantle, Nick
AU  - Freemantle N
AD  - Department of Primary Care and General Practice, University of Birmingham, 
      Birmingham, UK.
FAU - Eastaugh, Joanne
AU  - Eastaugh J
AD  - Medicines Evaluation Group, Centre for Health, University of York, York, UK.
FAU - Young, Phillip J
AU  - Young PJ
AD  - Health Sciences and Clinical Evaluation, University of York, York, UK.
FAU - Harrison, Jane
AU  - Harrison J
AD  - Medicines Evaluation Group, Centre for Health, University of York, York, UK.
LA  - eng
PT  - Journal Article
PL  - England
TA  - Cochrane Database Syst Rev
JT  - The Cochrane database of systematic reviews
JID - 100909747
PMC - PMC4234084
MID - EMS57133
EDAT- 2000/01/01 00:00
MHDA- 2000/01/01 00:00
PMCR- 2014/11/17
CRDT- 2014/11/21 06:00
PHST- 2014/11/21 06:00 [entrez]
PHST- 2000/01/01 00:00 [pubmed]
PHST- 2000/01/01 00:00 [medline]
PHST- 2014/11/17 00:00 [pmc-release]
AID - CD002131 [pii]
AID - 10.1002/14651858.CD002131 [doi]
PST - ppublish
SO  - Cochrane Database Syst Rev. 2000;(2):CD002131. doi: 10.1002/14651858.CD002131.