PMID- 25418427
OWN - NLM
STAT- MEDLINE
DCOM- 20160120
LR  - 20161125
IS  - 1540-8175 (Electronic)
IS  - 0742-2822 (Linking)
VI  - 32
IP  - 5
DP  - 2015 May
TI  - Relation of epicardial fat thickness to the severity of heart failure in patients 
      with nonischemic dilated cardiomyopathy.
PG  - 740-8
LID - 10.1111/echo.12796 [doi]
AB  - BACKGROUND: The aim of this study was to assess whether epicardial fat thickness 
      (EFT) is associated with the severity of heart failure in patients with 
      nonischemic dilated cardiomyopathy (NICMP). METHODS: The study group was composed 
      of 93 patients with NICMP and38 age- and sex-matched healty individuals as the 
      control group. The EFT was identified during end-systole at the point on the free 
      wall of the right ventricle. RESULTS: Patients with NICMP had significantly lower 
      mean EFT than those in the control group (4.1 +/- 0.8 vs. 6.1 +/- 1.8 mm, P < 0.001). 
      EFT was thinnest in patients with New York Heart Association (NYHA) functional 
      class III or IV (3.5 +/- 0.5, P < 0.001). There was a significant correlation 
      between EFT, left ventricle EF (r = 0.540 P < 0.001), and B-type natriuretic 
      peptide (BNP) (r = -0.695, P < 0.001) values in patients with NICMP. In addition, 
      when EFT was corrected for BMI, EFT/BMI was lower in patients with NYHA 
      functional class III-IV than patients with NYHA class I-II and control group 
      (0.13 +/- 0.01, 0.16 +/- 0.02, 0.23 +/- 0.04, respectively; P < 0.001). There was a 
      significant correlation between EFT/BMI, left ventricle EF (r = 0.489, P < 
      0.001), and BNP (r = -0.549, P < 0.001) in patients with NICMP. In multivariate 
      regression analysis, EFT (P = 0.009), BNP (P = 0.039), and left atrium volume 
      index (P = 0.039) were independently associated with impaired functional status. 
      CONCLUSION: Echocardiographic EFT is an inexpensive, simple, and readily 
      available marker that may be used to asses the severity of chronic heart failure 
      in patients with NICMP.
CI  - (c) 2014, Wiley Periodicals, Inc.
FAU - Tabakci, Mehmet Mustafa
AU  - Tabakci MM
AD  - Cardiology Department, Kartal Kosuyolu Cardiovascular Research and Training 
      Hospital, Istanbul, Turkey.
FAU - Durmus, Halil Ibrahim
AU  - Durmus HI
FAU - Avci, Anil
AU  - Avci A
FAU - Toprak, Cuneyt
AU  - Toprak C
FAU - Demir, Serdar
AU  - Demir S
FAU - Arslantas, Ugur
AU  - Arslantas U
FAU - Cersit, Sinan
AU  - Cersit S
FAU - Fidan, Serdar
AU  - Fidan S
FAU - Kulahcioglu, Seyhmus
AU  - Kulahcioglu S
FAU - Batgerel, Ulaankhuu
AU  - Batgerel U
FAU - Kargin, Ramazan
AU  - Kargin R
LA  - eng
PT  - Journal Article
DEP - 20141124
PL  - United States
TA  - Echocardiography
JT  - Echocardiography (Mount Kisco, N.Y.)
JID - 8511187
RN  - 114471-18-0 (Natriuretic Peptide, Brain)
SB  - IM
MH  - Adipose Tissue/*diagnostic imaging
MH  - Body Mass Index
MH  - Cardiomyopathy, Dilated/blood/complications/*diagnostic imaging
MH  - Female
MH  - Heart Failure/blood/complications/*diagnostic imaging
MH  - Heart Ventricles/diagnostic imaging
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Natriuretic Peptide, Brain/blood
MH  - Pericardium/*diagnostic imaging
MH  - Retrospective Studies
MH  - Severity of Illness Index
MH  - Ultrasonography
OTO - NOTNLM
OT  - dilated cardiomyopathy
OT  - echocardiography
OT  - ejection fraction
OT  - heart failure
EDAT- 2014/11/25 06:00
MHDA- 2016/01/21 06:00
CRDT- 2014/11/25 06:00
PHST- 2014/11/25 06:00 [entrez]
PHST- 2014/11/25 06:00 [pubmed]
PHST- 2016/01/21 06:00 [medline]
AID - 10.1111/echo.12796 [doi]
PST - ppublish
SO  - Echocardiography. 2015 May;32(5):740-8. doi: 10.1111/echo.12796. Epub 2014 Nov 
      24.