PMID- 25418641
OWN - NLM
STAT- MEDLINE
DCOM- 20161213
LR  - 20161230
IS  - 1726-4642 (Electronic)
IS  - 1726-4634 (Linking)
VI  - 31
IP  - 3
DP  - 2014 Jul-Sep
TI  - [Implementation of a telediagnostic system for tuberculosis and determination of 
      multi-drug resistance based in the MODS method in Trujillo, Peru].
PG  - 445-53
LID - S1726-46342014000300006 [pii]
AB  - OBJECTIVES: To implement a system for remote diagnosis of tuberculosis and 
      multidrug resistance (MDR) using the Microscopic-Observation Drug Susceptibility 
      Assay (MODS) method in the Mycobacteria Laboratory, Trujillo Center of Excellence 
      in Tuberculosis (CENEX-Trujillo). The system included a variant of an algorithm 
      for recognition of Mycobacterium tuberculosis recently reported from digital 
      images of MODS cultures of sputum samples. MATERIALS AND METHODS: The recognition 
      algorithm was optimized using a retraining statistical model based on digital 
      images of MODS cultures from CENEX-Trujillo. Images of 50 positive MODS cultures 
      of patients with suspected multidrug-resistant tuberculosis were obtained between 
      January and October 2012 in the CENEX-Trujillo. RESULTS: The sensitivity and 
      specificity to recognize strings of tuberculosis were 92.04% and 94.93% 
      respectively using objects. The sensitivity and specificity to determine a 
      positive tuberculosis field were 95.4% and 98.07% respectively using pictures. 
      CONCLUSIONS: The results demonstrated the feasibility of the implementation of 
      telediagnostics in remote locations, which may contribute to the early detection 
      of multidrug-resistant tuberculosis by MODS method.
FAU - Rodriguez, Luis
AU  - Rodriguez L
AD  - Centro de Excelencia en Tuberculosis Luz Caviedes Rojas, Hospital Regional 
      Docente de Trujillo, La Libertad, Peru
FAU - Alva, Alicia
AU  - Alva A
AD  - Laboratorio de Investigacion en Enfermedades Infecciosas, Laboratorio de 
      Investigacion y Desarrollo, Facultad de Ciencias y Filosofia, Universidad Peruana 
      Cayetano Heredia, Lima, Peru
FAU - Coronel, Jorge
AU  - Coronel J
AD  - Laboratorio de Investigacion en Enfermedades Infecciosas, Laboratorio de 
      Investigacion y Desarrollo, Facultad de Ciencias y Filosofia, Universidad Peruana 
      Cayetano Heredia, Lima, Peru
FAU - Caviedes, Luz
AU  - Caviedes L
AD  - Laboratorio de Investigacion en Enfermedades Infecciosas, Laboratorio de 
      Investigacion y Desarrollo, Facultad de Ciencias y Filosofia, Universidad Peruana 
      Cayetano Heredia, Lima, Peru
FAU - Mendoza-Ticona, Alberto
AU  - Mendoza-Ticona A
AD  - Instituto Nacional de Salud, Lima, Peru
FAU - Gilman, Robert
AU  - Gilman R
AD  - ONG A.B. PRISMA, Lima, Peru
FAU - Sheen, Patricia
AU  - Sheen P
AD  - Laboratorio de Investigacion en Enfermedades Infecciosas, Laboratorio de 
      Investigacion y Desarrollo, Facultad de Ciencias y Filosofia, Universidad Peruana 
      Cayetano Heredia, Lima, Peru
FAU - Zimic, Mirko
AU  - Zimic M
AD  - Laboratorio de Investigacion en Enfermedades Infecciosas, Laboratorio de 
      Investigacion y Desarrollo, Facultad de Ciencias y Filosofia, Universidad Peruana 
      Cayetano Heredia, Lima, Peru
LA  - spa
PT  - Journal Article
TT  - Implementacion de un sistema de telediagnostico de tuberculosis y determinacion 
      de multidrogorresistencia basada en el metodo Mods en Trujillo, Peru.
PL  - Peru
TA  - Rev Peru Med Exp Salud Publica
JT  - Revista peruana de medicina experimental y salud publica
JID - 101227566
SB  - IM
MH  - Algorithms
MH  - Bacteriological Techniques
MH  - Diagnostic Imaging
MH  - Humans
MH  - Microbial Sensitivity Tests
MH  - Mycobacterium tuberculosis/drug effects/growth & development
MH  - Peru
MH  - *Telemedicine
MH  - Tuberculosis/*diagnosis
MH  - Tuberculosis, Multidrug-Resistant/diagnosis
EDAT- 2014/11/25 06:00
MHDA- 2016/12/15 06:00
CRDT- 2014/11/25 06:00
PHST- 2014/03/31 00:00 [received]
PHST- 2014/08/06 00:00 [accepted]
PHST- 2014/11/25 06:00 [entrez]
PHST- 2014/11/25 06:00 [pubmed]
PHST- 2016/12/15 06:00 [medline]
AID - S1726-46342014000300006 [pii]
PST - ppublish
SO  - Rev Peru Med Exp Salud Publica. 2014 Jul-Sep;31(3):445-53.