PMID- 25422854
OWN - NLM
STAT- MEDLINE
DCOM- 20160122
LR  - 20150218
IS  - 2165-8110 (Electronic)
IS  - 2165-8102 (Linking)
VI  - 3
DP  - 2015
TI  - Comparative immunology of allergic responses.
PG  - 327-46
LID - 10.1146/annurev-animal-022114-110930 [doi]
AB  - Allergic responses occur in humans, rodents, non-human primates, avian species, 
      and all of the domestic animals. These responses are mediated by immunoglobulin E 
      (IgE) antibodies that bind to mast cells and cause release/synthesis of potent 
      mediators. Clinical syndromes include naturally occurring asthma in humans and 
      cats; atopic dermatitis in humans, dogs, horses, and several other species; food 
      allergies; and anaphylactic shock. Experimental induction of asthma in mice, 
      rats, monkeys, sheep, and cats has helped to reveal mechanisms of pathogenesis of 
      asthma in humans. All of these species share the ability to develop a rapid and 
      often fatal response to systemic administration of an allergen--anaphylactic 
      shock. Genetic predisposition to development of allergic disease (atopy) has been 
      demonstrated in humans, dogs, and horses. Application of mouse models of 
      IgE-mediated allergic asthma has provided evidence for a role of air pollutants 
      (ozone, diesel exhaust, environmental tobacco smoke) in enhanced sensitization to 
      allergens.
FAU - Gershwin, Laurel J
AU  - Gershwin LJ
AD  - School of Veterinary Medicine, University of California, Davis, California 95616; 
      email: ljgershwin@ucdavis.edu.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20141120
PL  - United States
TA  - Annu Rev Anim Biosci
JT  - Annual review of animal biosciences
JID - 101614024
RN  - 0 (Air Pollutants)
RN  - 0 (Allergens)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Air Pollutants/immunology
MH  - Allergens/immunology
MH  - Animals
MH  - Disease Models, Animal
MH  - Genetic Predisposition to Disease
MH  - Humans
MH  - Hypersensitivity/genetics/*immunology/veterinary
MH  - Immune System/physiology
MH  - Immunoglobulin E/immunology
MH  - Livestock
MH  - Species Specificity
OTO - NOTNLM
OT  - IgE
OT  - anaphylaxis
OT  - animal models
OT  - asthma
EDAT- 2014/11/26 06:00
MHDA- 2016/01/23 06:00
CRDT- 2014/11/26 06:00
PHST- 2014/11/26 06:00 [entrez]
PHST- 2014/11/26 06:00 [pubmed]
PHST- 2016/01/23 06:00 [medline]
AID - 10.1146/annurev-animal-022114-110930 [doi]
PST - ppublish
SO  - Annu Rev Anim Biosci. 2015;3:327-46. doi: 10.1146/annurev-animal-022114-110930. 
      Epub 2014 Nov 20.