PMID- 25423554
OWN - NLM
STAT- MEDLINE
DCOM- 20150518
LR  - 20151119
IS  - 1532-3145 (Electronic)
IS  - 0363-8715 (Linking)
VI  - 39
IP  - 2
DP  - 2015 Mar-Apr
TI  - Right ventricular stress-induced perfusion defects and late gadolinium 
      enhancement in coronary artery disease.
PG  - 185-8
LID - 10.1097/RCT.0000000000000175 [doi]
AB  - OBJECTIVE: The assessment of right ventricular (RV) perfusion defects has 
      remained challenging during vasodilator stress perfusion with cardiovascular 
      magnetic resonance (CMR). The significance of RV signal abnormalities during 
      vasodilator stress perfusion and late gadolinium-enhanced CMR is yet uncertain. 
      METHODS: Among 61 individuals who underwent adenosine CMR stress testing before 
      cardiac catheterization, we assessed the severity of coronary artery stenoses, 
      mortality, the presence of stress and rest perfusion defects, as well as the 
      presence of late gadolinium enhancement (LGE). RESULTS: Right ventricular 
      stress-induced perfusion defects were positively associated with left anterior 
      descending artery and proximal right coronary artery stenoses but were negatively 
      associated with left circumflex artery stenoses. The presence of RVLGE was 
      associated with mortality, but 77% of those with RVLGE also had left ventricular 
      LGE. CONCLUSIONS: Proximal right coronary artery and left anterior descending 
      artery stenoses are positively associated, whereas left circumflex artery 
      stenoses are negatively associated with RV stress-induced perfusion defects. 
      Right ventricular LGE was associated with mortality, but further study is needed 
      to determine whether this is independent of left ventricular LGE.
FAU - Milks, Michael Wesley
AU  - Milks MW
AD  - From the *Department of Internal Medicine, and daggerSection of Cardiology, Wake 
      Forest School of Medicine, Winston-Salem, NC; double daggerDivision of Cardiology, Department 
      of Internal Medicine, University of Mississippi Medical Center, Jackson, MS.
FAU - Upadhya, Bharathi
AU  - Upadhya B
FAU - Hall, Michael E
AU  - Hall ME
FAU - Vasu, Sujethra
AU  - Vasu S
FAU - Hundley, William Gregory
AU  - Hundley WG
FAU - Stacey, Richard Brandon
AU  - Stacey RB
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Comput Assist Tomogr
JT  - Journal of computer assisted tomography
JID - 7703942
RN  - 0 (Contrast Media)
RN  - AU0V1LM3JT (Gadolinium)
SB  - IM
MH  - *Contrast Media
MH  - Coronary Artery Disease/*physiopathology
MH  - Coronary Circulation
MH  - Exercise Test
MH  - Female
MH  - *Gadolinium
MH  - Humans
MH  - Image Enhancement
MH  - *Magnetic Resonance Imaging/methods
MH  - Male
MH  - Middle Aged
MH  - Ventricular Dysfunction, Right/*physiopathology
EDAT- 2014/11/26 06:00
MHDA- 2015/05/20 06:00
CRDT- 2014/11/26 06:00
PHST- 2014/11/26 06:00 [entrez]
PHST- 2014/11/26 06:00 [pubmed]
PHST- 2015/05/20 06:00 [medline]
AID - 10.1097/RCT.0000000000000175 [doi]
PST - ppublish
SO  - J Comput Assist Tomogr. 2015 Mar-Apr;39(2):185-8. doi: 
      10.1097/RCT.0000000000000175.