PMID- 2542358 OWN - NLM STAT- MEDLINE DCOM- 19890703 LR - 20210526 IS - 0095-1137 (Print) IS - 1098-660X (Electronic) IS - 0095-1137 (Linking) VI - 27 IP - 4 DP - 1989 Apr TI - Seroepidemiology of human herpesvirus 6 infection in normal children and adults. PG - 651-3 AB - Sera from normal subjects were examined for reactivity to human herpesvirus 6 (HHV-6) by the anticomplement immunofluorescence test. Of a total of 179 serum specimens from donors aged from under 10 to 59 years, 141 specimens showed positive reactivity against HHV-6. The positive rate was 70 to 83% for all age groups, and there were no substantial differences in the positive rates. Sera from younger children aged from 0 to 21 months were then examined in detail. The antibody-positive rate of children aged from 0 to 5 months decreased from 52 to 5%, but it gradually increased by 12 months. Almost all children had the antibody against this virus after 13 months of age. FAU - Okuno, T AU - Okuno T AD - Department of Virology, Osaka University, Japan. FAU - Takahashi, K AU - Takahashi K FAU - Balachandra, K AU - Balachandra K FAU - Shiraki, K AU - Shiraki K FAU - Yamanishi, K AU - Yamanishi K FAU - Takahashi, M AU - Takahashi M FAU - Baba, K AU - Baba K LA - eng PT - Journal Article PL - United States TA - J Clin Microbiol JT - Journal of clinical microbiology JID - 7505564 RN - 0 (Antibodies, Viral) SB - IM MH - Adolescent MH - Adult MH - Age Factors MH - Antibodies, Viral/*analysis MH - Child MH - Child, Preschool MH - Cross Reactions MH - Fluorescent Antibody Technique MH - Herpesviridae/classification/*immunology MH - Herpesviridae Infections/epidemiology/*immunology MH - Humans MH - Infant MH - Middle Aged MH - United States PMC - PMC267390 EDAT- 1989/04/01 00:00 MHDA- 1989/04/01 00:01 PMCR- 1989/04/01 CRDT- 1989/04/01 00:00 PHST- 1989/04/01 00:00 [pubmed] PHST- 1989/04/01 00:01 [medline] PHST- 1989/04/01 00:00 [entrez] PHST- 1989/04/01 00:00 [pmc-release] AID - 10.1128/jcm.27.4.651-653.1989 [doi] PST - ppublish SO - J Clin Microbiol. 1989 Apr;27(4):651-3. doi: 10.1128/jcm.27.4.651-653.1989.