PMID- 25429202
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20141127
LR  - 20200930
IS  - 1177-5467 (Print)
IS  - 1177-5483 (Electronic)
IS  - 1177-5467 (Linking)
VI  - 8
DP  - 2014
TI  - Diagnostic challenges in primary orbital fibrosarcoma: a case report.
PG  - 2319-23
LID - 10.2147/OPTH.S70843 [doi]
AB  - Fibrosarcoma is a rare and malignant spindle cell tumor of mesenchymal origin 
      that infrequently presents in the orbit. Evolving diagnostic criteria confound 
      the identification of these tumors, as well as the interpretation of previous 
      studies on this unusual entity. We report a case of a 66-year-old man with a mass 
      on his left inferior orbit, with associated paresthesia. A computed tomography 
      (CT) scan showed a lesion on the left anteroinferomedial orbit, with bone 
      erosion. An en bloc surgical excision followed by a thorough immunohistologic 
      evaluation allowed diagnosis of an orbital fibrosarcoma. The patient has had no 
      recurrence after 14 months of follow up. Once a commonly identified soft tissue 
      malignancy, fibrosarcoma has become a diagnosis of exclusion as a result of 
      improved diagnostic and classification techniques, such as immunohistochemistry 
      and fluorescence in situ hybridization (FISH). This type of soft tissue tumor is 
      now an uncommon entity, and we report the first case of a primary orbital 
      fibrosarcoma in an adult, using modern diagnostic and classification methods.
FAU - Scruggs, Brittni A
AU  - Scruggs BA
AD  - Department of Ophthalmology, School of Medicine, Tulane University, New Orleans, 
      LA, USA.
FAU - Ho, Son T
AU  - Ho ST
AD  - Department of Ophthalmology, School of Medicine, Tulane University, New Orleans, 
      LA, USA.
FAU - Valenzuela, Alejandra A
AU  - Valenzuela AA
AD  - Department of Ophthalmology, School of Medicine, Tulane University, New Orleans, 
      LA, USA.
LA  - eng
PT  - Case Reports
DEP - 20141120
PL  - New Zealand
TA  - Clin Ophthalmol
JT  - Clinical ophthalmology (Auckland, N.Z.)
JID - 101321512
PMC - PMC4242685
OTO - NOTNLM
OT  - fibroblasts
OT  - mesenchymal tumor
OT  - soft tissue malignancy
OT  - spindle cell orbital tumor
EDAT- 2014/11/28 06:00
MHDA- 2014/11/28 06:01
PMCR- 2014/11/20
CRDT- 2014/11/28 06:00
PHST- 2014/11/28 06:00 [entrez]
PHST- 2014/11/28 06:00 [pubmed]
PHST- 2014/11/28 06:01 [medline]
PHST- 2014/11/20 00:00 [pmc-release]
AID - opth-8-2319 [pii]
AID - 10.2147/OPTH.S70843 [doi]
PST - epublish
SO  - Clin Ophthalmol. 2014 Nov 20;8:2319-23. doi: 10.2147/OPTH.S70843. eCollection 
      2014.