PMID- 25429208
OWN - NLM
STAT- MEDLINE
DCOM- 20150713
LR  - 20181113
IS  - 1178-1998 (Electronic)
IS  - 1176-9092 (Print)
IS  - 1176-9092 (Linking)
VI  - 9
DP  - 2014
TI  - Achieving glycemic control in elderly patients with type 2 diabetes: a critical 
      comparison of current options.
PG  - 1963-80
LID - 10.2147/CIA.S53482 [doi]
AB  - The prevalence of type 2 diabetes mellitus (T2DM) is increasing in the elderly. 
      Because of the unique characteristics of elderly people with T2DM, therapeutic 
      strategy and focus should be tailored to suit this population. This article 
      reviews the guidelines and studies related to older people with T2DM worldwide. A 
      few important themes are generalized: 1) the functional and cognitive status is 
      critical for older people with T2DM considering their life expectancy compared to 
      younger counterparts; 2) both severe hypoglycemia and persistent hyperglycemia 
      are deleterious to older adults with T2DM, and both conditions should be avoided 
      when determining therapeutic goals; 3) recently developed guidelines emphasize 
      the avoidance of hypoglycemic episodes in older people, even in the absence of 
      symptoms. In addition, we raise the concern of glycemic variability, and discuss 
      the rationale for the selection of current options in managing this patient 
      population.
FAU - Du, Ye-Fong
AU  - Du YF
AD  - Division of Endocrinology and Metabolism, Department of Internal Medicine, 
      National Cheng Kung University Hospital, Tainan, Taiwan.
FAU - Ou, Horng-Yih
AU  - Ou HY
AD  - Division of Endocrinology and Metabolism, Department of Internal Medicine, 
      National Cheng Kung University Hospital, Tainan, Taiwan.
FAU - Beverly, Elizabeth A
AU  - Beverly EA
AD  - Department of Social Medicine, Ohio University Heritage College of Osteopathic 
      Medicine, Athens, OH, USA.
FAU - Chiu, Ching-Ju
AU  - Chiu CJ
AD  - Institute of Gerontology, College of Medicine, National Cheng Kung University, 
      Tainan, Taiwan.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20141118
PL  - New Zealand
TA  - Clin Interv Aging
JT  - Clinical interventions in aging
JID - 101273480
RN  - 0 (Blood Glucose)
RN  - 0 (Hypoglycemic Agents)
SB  - IM
MH  - Blood Glucose
MH  - Cognition
MH  - Diabetes Mellitus, Type 2/*drug therapy
MH  - Diet
MH  - Drug Therapy, Combination
MH  - Exercise
MH  - Humans
MH  - Hyperglycemia/prevention & control
MH  - Hypoglycemia/prevention & control
MH  - Hypoglycemic Agents/administration & dosage/adverse effects/*therapeutic use
MH  - Life Expectancy
MH  - Practice Guidelines as Topic
MH  - Risk Factors
PMC - PMC4241951
OTO - NOTNLM
OT  - blood glucose
OT  - frailty
OT  - glycemic target
OT  - glycemic variability
EDAT- 2014/11/28 06:00
MHDA- 2015/07/15 06:00
PMCR- 2014/11/18
CRDT- 2014/11/28 06:00
PHST- 2014/11/28 06:00 [entrez]
PHST- 2014/11/28 06:00 [pubmed]
PHST- 2015/07/15 06:00 [medline]
PHST- 2014/11/18 00:00 [pmc-release]
AID - cia-9-1963 [pii]
AID - 10.2147/CIA.S53482 [doi]
PST - epublish
SO  - Clin Interv Aging. 2014 Nov 18;9:1963-80. doi: 10.2147/CIA.S53482. eCollection 
      2014.