PMID- 25434129
OWN - NLM
STAT- MEDLINE
DCOM- 20150901
LR  - 20190923
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 32
IP  - 8
DP  - 2014 Aug
TI  - [Matrix effect and application of field-amplified sample injection in the 
      analysis of four tetracyclines in waters by capillary electrohoresis].
PG  - 897-903
AB  - The system abilities of two chromatographic techniques, capillary electrophoresis 
      (CE) and high performance liquid chromatography (HPLC), were compared for the 
      analysis of four tetracyclines (tetracycline, chlorotetracycline, oxytetracycline 
      and doxycycline). The pH, concentration of background electrolyte (BGE) were 
      optimized for the analysis of the standard mixture sample, meanwhile, the effects 
      of separation voltage and water matrix (pH value and hardness) effects were 
      investigated. In hydrodynamic injection (HDI) mode, a good quantitative linearity 
      and baseline separation within 9. 0 min were obtained for the four tetracyclines 
      at the optimal conditions; the analytical time was about half of that of HPLC. 
      The limits of detection (LODs) were in the range of 0. 28 - 0. 62 mg/L, and the 
      relative standard deviations (RSDs) (n= 6) of migration time and peak area were 
      0. 42% - 0. 56% and 2. 24% - 2. 95%, respectively. The obtained recoveries spiked 
      in tap water and fishpond water were at the ranges of 96. 3% - 107. 2% and 87. 1% 
      - 105. 2%, respectively. In addition, the stacking method, field-amplified sample 
      injection (FASI), was employed to improve the sensitivity, and the LOD was down 
      to the range of 17.8-35.5 mug/L. With FASI stacking, the RSDs (n=6) of migration 
      time and peak area were 0. 85%-0. 95% and 1. 69%-3.43%, respectively. Due to the 
      advantages of simple sample pretreatment and fast speed, CE is promising in the 
      analysis of the antibiotics in environmental water.
LA  - chi
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Tetracyclines)
RN  - 059QF0KO0R (Water)
SB  - IM
MH  - Anti-Bacterial Agents/*analysis
MH  - *Electrophoresis, Capillary
MH  - Limit of Detection
MH  - Tetracyclines/*analysis
MH  - Water/*analysis
EDAT- 2014/12/02 06:00
MHDA- 2015/09/02 06:00
CRDT- 2014/12/02 06:00
PHST- 2014/12/02 06:00 [entrez]
PHST- 2014/12/02 06:00 [pubmed]
PHST- 2015/09/02 06:00 [medline]
AID - 10.3724/sp.j.1123.2014.03044 [doi]
PST - ppublish
SO  - Se Pu. 2014 Aug;32(8):897-903. doi: 10.3724/sp.j.1123.2014.03044.