PMID- 25438376
OWN - NLM
STAT- MEDLINE
DCOM- 20150113
LR  - 20141202
IS  - 1660-9379 (Print)
IS  - 1660-9379 (Linking)
VI  - 10
IP  - 446
DP  - 2014 Oct 15
TI  - [Subcutaneous antibiotic administration in elderly patients].
PG  - 1924, 1926-9
AB  - Although off-label, subcutaneous (SC) antibiotic administration is not 
      infrequent, particularly among geriatric and palliative-care patients for whom 
      other routes of administration are difficult to establish. Subcutaneous 
      ceftriaxone is the most frequently prescribed antibiotic and it has been approved 
      by some local committees given its favorable pharmacological parameters and 
      relatively low subcutaneous toxicity. Yet pharmacologic and clinical data are 
      lacking. No study has demonstrated non-inferiority of the subcutaneous route in 
      comparison to other parenteral routes of administration. Randomized controlled 
      trials are needed to assess the efficacy and tolerability of subcutaneous 
      antibiotic administration given its frequent use in an aging population.
FAU - Gassler, V
AU  - Gassler V
FAU - Stirnemann, J
AU  - Stirnemann J
FAU - Huttner, A
AU  - Huttner A
FAU - Prendki, V
AU  - Prendki V
LA  - fre
PT  - English Abstract
PT  - Journal Article
PT  - Review
TT  - Antibiotherapie par voie sous-cutanee chez le patient age.
PL  - Switzerland
TA  - Rev Med Suisse
JT  - Revue medicale suisse
JID - 101219148
RN  - 0 (Anti-Bacterial Agents)
SB  - IM
MH  - Age Factors
MH  - *Aged
MH  - Aged, 80 and over
MH  - Anti-Bacterial Agents/*administration & dosage
MH  - Antibiotic Prophylaxis/standards
MH  - Humans
MH  - Injections, Subcutaneous
EDAT- 2014/12/03 06:00
MHDA- 2015/01/15 06:00
CRDT- 2014/12/03 06:00
PHST- 2014/12/03 06:00 [entrez]
PHST- 2014/12/03 06:00 [pubmed]
PHST- 2015/01/15 06:00 [medline]
PST - ppublish
SO  - Rev Med Suisse. 2014 Oct 15;10(446):1924, 1926-9.