PMID- 25438605 OWN - NLM STAT- MEDLINE DCOM- 20141231 LR - 20191113 IS - 0016-6758 (Print) IS - 0016-6758 (Linking) VI - 49 IP - 12 DP - 2013 Dec TI - [Brain-derived neurotrophic factor gene (BDNF) polymorphism among Moscow citizens]. PG - 1432-5 AB - Recent studies showed that brain-derived neurotrophic factor (BDNF) can participate in pathogenesis of various CNS disorders, being connected with proliferation, differentiation, and survival of neurons. In present study, analysis of occurrence rate was performed for three single nucleotide polymorphisms (SNPs) located in BDNF gene (rs6267 (A/G) allele A-0.265; rs2049046 (A/T) allele A-0.407; rs11030107 (A/G) allele A-0.872) in randomized selection of Moscow citizens. Linkage disequilibrium of rs6165 and rs2049046 loci was shown. Differences in allele frequencies in studied selection and populations of other re- gions were discovered. FAU - Kokaeva, Z G AU - Kokaeva ZG FAU - Kochetkova, T O AU - Kochetkova TO FAU - Afonchikova, E V AU - Afonchikova EV FAU - Kondratyeva, N S AU - Kondratyeva NS FAU - Klimov, E A AU - Klimov EA LA - rus PT - Journal Article PL - Russia (Federation) TA - Genetika JT - Genetika JID - 0047354 RN - 0 (Brain-Derived Neurotrophic Factor) RN - 7171WSG8A2 (BDNF protein, human) SB - IM MH - Adolescent MH - Adult MH - Brain-Derived Neurotrophic Factor/*genetics MH - Female MH - Gene Frequency MH - Humans MH - Linkage Disequilibrium MH - Male MH - Middle Aged MH - Moscow MH - *Polymorphism, Single Nucleotide EDAT- 2014/12/03 06:00 MHDA- 2015/01/01 06:00 CRDT- 2014/12/03 06:00 PHST- 2014/12/03 06:00 [entrez] PHST- 2014/12/03 06:00 [pubmed] PHST- 2015/01/01 06:00 [medline] AID - 10.7868/s0016675813120047 [doi] PST - ppublish SO - Genetika. 2013 Dec;49(12):1432-5. doi: 10.7868/s0016675813120047.