PMID- 25442525 OWN - NLM STAT- MEDLINE DCOM- 20150701 LR - 20220409 IS - 1873-7072 (Electronic) IS - 0308-8146 (Linking) VI - 172 DP - 2015 Apr 1 TI - Anti-inflammatory and antioxidative activity of anthocyanins from purple basil leaves induced by selected abiotic elicitors. PG - 71-7 LID - S0308-8146(14)01410-1 [pii] LID - 10.1016/j.foodchem.2014.09.043 [doi] AB - This paper investigates changes in the anti-inflammatory and antioxidative activity of anthocyanins from purple basil (Ocimum basilicum L.) leaves induced by arachidonic acid (AA), jasmonic acid (JA) and beta-aminobutyric acid (BABA). The anthocyanins content was significantly increased by all elicitors used in this study; however, no increase was observed in the antioxidant activity of the analyzed extracts. Additionally, a significant decrease by about 50% in the ability to chelate Fe(II) was noted. Further, an increase in the potential anti-inflammatory activity of basil anthocyanins was observed after treatment with each the abiotic elicitor. The IC50 value for lipoxygenase inhibition was almost twice as low after elicitation as that of the control. Also, cyclooxygenase inhibition by anthocyanins was stimulated by abiotic elicitors, except for JA-sample. Additionally, HPLC-analysis indicated that elicitation with AA, JA and BABA caused increases in content most of all anthocyanin compounds. CI - Copyright (c) 2014 Elsevier Ltd. All rights reserved. FAU - Szymanowska, Urszula AU - Szymanowska U AD - Department of Biochemistry and Food Chemistry, University of Life Sciences, Skromna Str. 8, 20-704 Lublin, Poland. FAU - Zlotek, Urszula AU - Zlotek U AD - Department of Biochemistry and Food Chemistry, University of Life Sciences, Skromna Str. 8, 20-704 Lublin, Poland. Electronic address: urszula.zlotek@up.lublin.pl. FAU - Karas, Monika AU - Karas M AD - Department of Biochemistry and Food Chemistry, University of Life Sciences, Skromna Str. 8, 20-704 Lublin, Poland. FAU - Baraniak, Barbara AU - Baraniak B AD - Department of Biochemistry and Food Chemistry, University of Life Sciences, Skromna Str. 8, 20-704 Lublin, Poland. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20140917 PL - England TA - Food Chem JT - Food chemistry JID - 7702639 RN - 0 (Aminobutyrates) RN - 0 (Anthocyanins) RN - 0 (Anti-Inflammatory Agents) RN - 0 (Antioxidants) RN - 0 (Cyclopentanes) RN - 0 (Oxylipins) RN - 0 (Plant Extracts) RN - 27YG812J1I (Arachidonic Acid) RN - 4282SA5CTS (3-aminobutyric acid) RN - 6RI5N05OWW (jasmonic acid) SB - IM MH - Aminobutyrates/*pharmacology MH - Anthocyanins/analysis MH - Anti-Inflammatory Agents/*analysis MH - Antioxidants/*analysis MH - Arachidonic Acid/*pharmacology MH - Chromatography, High Pressure Liquid MH - Cyclopentanes/*pharmacology MH - Ocimum basilicum/*chemistry/*drug effects MH - Oxylipins/*pharmacology MH - Plant Extracts/*analysis MH - Plant Leaves/chemistry/drug effects OTO - NOTNLM OT - Anthocyanins OT - Antioxidant properties OT - Elicitation OT - Enzyme inhibition OT - Purple basil EDAT- 2014/12/03 06:00 MHDA- 2015/07/02 06:00 CRDT- 2014/12/03 06:00 PHST- 2013/05/06 00:00 [received] PHST- 2014/05/14 00:00 [revised] PHST- 2014/09/10 00:00 [accepted] PHST- 2014/12/03 06:00 [entrez] PHST- 2014/12/03 06:00 [pubmed] PHST- 2015/07/02 06:00 [medline] AID - S0308-8146(14)01410-1 [pii] AID - 10.1016/j.foodchem.2014.09.043 [doi] PST - ppublish SO - Food Chem. 2015 Apr 1;172:71-7. doi: 10.1016/j.foodchem.2014.09.043. Epub 2014 Sep 17.