PMID- 25454151
OWN - NLM
STAT- MEDLINE
DCOM- 20150728
LR  - 20181202
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1370
DP  - 2014 Nov 28
TI  - Rapid analysis of water- and fat-soluble vitamins by electrokinetic 
      chromatography with polymeric micelle as pseudostationary phase.
PG  - 263-9
LID - S0021-9673(14)01638-0 [pii]
LID - 10.1016/j.chroma.2014.10.047 [doi]
AB  - A novel polymeric micelle, formed by random copolymer poly (stearyl 
      methacrylate-co-methacrylic acid) (P(SMA-co-MAA)) has been used as 
      pseudostationary phase (PSP) in electrokinetic chromatography (EKC) for 
      simultaneous and rapid determination of 11 kinds of water- and fat-soluble 
      vitamins in this work. The running buffer consisting of 1% (w/v) P(SMA-co-MAA), 
      10% (v/v) 1-butanol, 20% (v/v) acetonitrile, and 30 mM Palitzsch buffer solution 
      (pH 9.2) was applied to improve the selectivity and efficiency, as well as to 
      shorten analysis time. 1-Butanol and acetonitrile as the organic solvent 
      modifiers played the most important roles for rapid separation of these vitamins. 
      The effects of organic solvents on microstructure of the polymeric micelle were 
      investigated. The organic solvents swell the polymeric micelle by three folds, 
      lower down the surface charge density and enhance the microenviromental polarity 
      of the polymeric micelle. The 11 kinds of water- and fat-soluble vitamins could 
      be baseline separated within 13 min. The method was applied to determine water- 
      and fat-soluble vitamins in commercial vitamin sample; the recoveries were 
      between 93% and 111% with the relative standard derivations (RSDs) less than 5%. 
      The determination results matched the label claim.
CI  - Copyright (c) 2014 Elsevier B.V. All rights reserved.
FAU - Ni, Xinjiong
AU  - Ni X
AD  - The Key Laboratory of Food Colloids and Biotechnology, Ministry of Education, 
      School of Chemical and Material Engineering, Jiangnan University, Wuxi 214122, PR 
      China.
FAU - Xing, Xiaoping
AU  - Xing X
AD  - Chemical and Biological Engineering College, Yancheng Institute of Technology, 
      Yancheng 224051, PR China.
FAU - Cao, Yuhua
AU  - Cao Y
AD  - The Key Laboratory of Food Colloids and Biotechnology, Ministry of Education, 
      School of Chemical and Material Engineering, Jiangnan University, Wuxi 214122, PR 
      China. Electronic address: yuhuacao64@gmail.com.
FAU - Cao, Guangqun
AU  - Cao G
AD  - The Key Laboratory of Food Colloids and Biotechnology, Ministry of Education, 
      School of Chemical and Material Engineering, Jiangnan University, Wuxi 214122, PR 
      China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20141024
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Fats)
RN  - 0 (Polymers)
RN  - 0 (Solvents)
RN  - 0 (Vitamins)
RN  - 059QF0KO0R (Water)
SB  - IM
MH  - Chromatography, Micellar Electrokinetic Capillary/instrumentation/*methods
MH  - Fats/chemistry
MH  - Hydrogen-Ion Concentration
MH  - Limit of Detection
MH  - Polymers
MH  - Reproducibility of Results
MH  - Solubility
MH  - Solvents/analysis
MH  - Temperature
MH  - Time Factors
MH  - Vitamins/*analysis
MH  - Water/chemistry
OTO - NOTNLM
OT  - Microstructure
OT  - Organic solvent modifier
OT  - Polymeric micelle
OT  - Vitamins
EDAT- 2014/12/03 06:00
MHDA- 2015/07/29 06:00
CRDT- 2014/12/03 06:00
PHST- 2014/08/27 00:00 [received]
PHST- 2014/10/16 00:00 [revised]
PHST- 2014/10/17 00:00 [accepted]
PHST- 2014/12/03 06:00 [entrez]
PHST- 2014/12/03 06:00 [pubmed]
PHST- 2015/07/29 06:00 [medline]
AID - S0021-9673(14)01638-0 [pii]
AID - 10.1016/j.chroma.2014.10.047 [doi]
PST - ppublish
SO  - J Chromatogr A. 2014 Nov 28;1370:263-9. doi: 10.1016/j.chroma.2014.10.047. Epub 
      2014 Oct 24.