PMID- 25457512
OWN - NLM
STAT- MEDLINE
DCOM- 20150722
LR  - 20141203
IS  - 1873-1716 (Electronic)
IS  - 0167-5877 (Linking)
VI  - 117
IP  - 3-4
DP  - 2014 Dec 1
TI  - Mixed treatment comparison meta-analysis of porcine circovirus type 2 (PCV2) 
      vaccines used in piglets.
PG  - 413-24
LID - S0167-5877(14)00344-4 [pii]
LID - 10.1016/j.prevetmed.2014.10.006 [doi]
AB  - Porcine circovirus type 2 (PCV2) vaccination is globally one of the most commonly 
      used intervention strategies in growing pigs since several products became 
      commercially available in 2006. While multiple trials have described the efficacy 
      of individual PCV2 vaccines relative to non-vaccination, few studies provide 
      product-to-product comparisons of efficacy. Given the well-documented efficacy of 
      PCV2 vaccines, information about the comparative efficacy of available vaccines 
      is more relevant to producers and veterinarians than comparison to 
      non-vaccination. The objective of this study was to provide comparative estimates 
      of changes in average daily gain effect associated with the use of the 
      commercially available PCV2 vaccines. PubMed, CAB Abstracts, AGRICOLA, the USA 
      Department of Agriculture Center for Veterinary Biologics database of licenses 
      and provisions, and the proceedings of the Annual Meeting of the American 
      Association of Swine Veterinarians, the Allen D. Leman Swine Conference, the Iowa 
      State University Swine Disease Conference for Swine Practitioners, and the 
      International Pig Veterinary Society Congress were used as the sources of 
      information. Trials of licensed PCV2 vaccines administered according to 
      manufacturers' specifications to intensively raised piglets with a known herd 
      porcine reproductive and respiratory syndrome virus (PRRSV) status were 
      considered relevant to the meta-analysis. Relevant studies had to report average 
      daily gain (ADG) from weaning to finish and PCV2 infection had to be naturally 
      occurring.
CI  - Copyright (c) 2014 Elsevier B.V. All rights reserved.
FAU - da Silva, N
AU  - da Silva N
AD  - Department of Statistics, Iowa State University College of Liberal Arts and 
      Sciences, Ames, IA 50011, United States.
FAU - Carriquiry, A
AU  - Carriquiry A
AD  - Department of Statistics, Iowa State University College of Liberal Arts and 
      Sciences, Ames, IA 50011, United States.
FAU - O'Neill, K
AU  - O'Neill K
AD  - Department of Veterinary Diagnostics and Production Animal Medicine, Iowa State 
      University College of Veterinary Medicine, 1600 South 16th Street, Ames, IA 
      50011, United States.
FAU - Opriessnig, T
AU  - Opriessnig T
AD  - Department of Veterinary Diagnostics and Production Animal Medicine, Iowa State 
      University College of Veterinary Medicine, 1600 South 16th Street, Ames, IA 
      50011, United States; The Roslin Institute and The Royal (Dick) School of 
      Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, 
      Scotland, UK.
FAU - O'Connor, A M
AU  - O'Connor AM
AD  - Department of Veterinary Diagnostics and Production Animal Medicine, Iowa State 
      University College of Veterinary Medicine, 1600 South 16th Street, Ames, IA 
      50011, United States. Electronic address: oconnor@iastate.edu.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
DEP - 20141031
PL  - Netherlands
TA  - Prev Vet Med
JT  - Preventive veterinary medicine
JID - 8217463
RN  - 0 (Viral Vaccines)
SB  - IM
CIN - Prev Vet Med. 2015 Apr 1;119(1-2):94-5. PMID: 25681863
CIN - Prev Vet Med. 2015 Apr 1;119(1-2):93. PMID: 25697365
MH  - Animals
MH  - Porcine Reproductive and Respiratory Syndrome/*prevention & control/virology
MH  - Porcine respiratory and reproductive syndrome virus/*immunology
MH  - Swine
MH  - Viral Vaccines/*pharmacology
OTO - NOTNLM
OT  - Bayesian inference
OT  - Mixed treatment comparison meta-analysis
OT  - PCV2
OT  - Pigs
OT  - Vaccination
EDAT- 2014/12/03 06:00
MHDA- 2015/07/23 06:00
CRDT- 2014/12/03 06:00
PHST- 2014/02/21 00:00 [received]
PHST- 2014/10/04 00:00 [revised]
PHST- 2014/10/07 00:00 [accepted]
PHST- 2014/12/03 06:00 [entrez]
PHST- 2014/12/03 06:00 [pubmed]
PHST- 2015/07/23 06:00 [medline]
AID - S0167-5877(14)00344-4 [pii]
AID - 10.1016/j.prevetmed.2014.10.006 [doi]
PST - ppublish
SO  - Prev Vet Med. 2014 Dec 1;117(3-4):413-24. doi: 10.1016/j.prevetmed.2014.10.006. 
      Epub 2014 Oct 31.