PMID- 25460621
OWN - NLM
STAT- MEDLINE
DCOM- 20150202
LR  - 20181113
IS  - 1096-0953 (Electronic)
IS  - 0013-9351 (Print)
IS  - 0013-9351 (Linking)
VI  - 136
DP  - 2015 Jan
TI  - Concentrations of persistent organic pollutants in California women's serum and 
      residential dust.
PG  - 57-66
LID - S0013-9351(14)00372-7 [pii]
LID - 10.1016/j.envres.2014.10.009 [doi]
AB  - BACKGROUND: Humans are exposed to persistent organic pollutants (POPs) through 
      various routes, including consumption of contaminated food and accidental 
      ingestion of settled dust. OBJECTIVES: We aimed to identify key routes of 
      exposure to organochlorine pesticides, polychlorinated biphenyls (PCBs), and 
      polybrominated diphenyl ethers (PBDEs) in California women of reproductive age. 
      METHODS: Blood was collected from 48 mothers participating in the California 
      Childhood Leukemia Study from 2006 to 2007 and analyzed for POPs using gas 
      chromatography-mass spectrometry. Multivariable linear regression models of 
      natural-log transformed serum concentrations were used to identify determinants 
      of exposure from available questionnaire information on dietary habits, 
      reproductive history, and demographic characteristics, as well as vacuum cleaner 
      dust-POP levels. RESULTS: After adjusting for blood lipid levels, age, body mass 
      index, cumulative lactation, and sampling date, serum concentrations of multiple 
      major PCBs were positively associated with fish consumption, but not dust-PCB 
      levels. After adjusting for blood lipid levels, Hispanic ethnicity, country of 
      origin, and household annual income, serum concentrations of multiple major PBDEs 
      were positively associated with dust-PBDE levels. CONCLUSIONS: Our findings 
      suggest that the relative contribution of specific exposure routes to total POP 
      intake varies by chemical class, with dust being a relatively important source of 
      PBDEs and diet being a relatively important source of PCBs.
CI  - Copyright (c) 2014 Elsevier Inc. All rights reserved.
FAU - Whitehead, Todd P
AU  - Whitehead TP
AD  - School of Public Health, University of California Berkeley, 50 University Hall, 
      Berkeley, CA 94720, USA. Electronic address: ToddPWhitehead@Berkeley.edu.
FAU - Crispo Smith, Sabrina
AU  - Crispo Smith S
AD  - Environmental Chemistry Laboratory, California Department of Toxic Substances 
      Control, 700 Heinz Ave, Berkeley, CA 94710, USA; Sequoia Foundation, 2166 Avenida 
      De La Playa, La Jolla, CA 92037, USA. Electronic address: 
      Sabrina.CrispoSmith@DTSC.CA.gov.
FAU - Park, June-Soo
AU  - Park JS
AD  - Environmental Chemistry Laboratory, California Department of Toxic Substances 
      Control, 700 Heinz Ave, Berkeley, CA 94710, USA. Electronic address: 
      June-Soo.Park@DTSC.CA.gov.
FAU - Petreas, Myrto X
AU  - Petreas MX
AD  - Environmental Chemistry Laboratory, California Department of Toxic Substances 
      Control, 700 Heinz Ave, Berkeley, CA 94710, USA. Electronic address: 
      Myrto.Petreas@DTSC.CA.gov.
FAU - Rappaport, Stephen M
AU  - Rappaport SM
AD  - School of Public Health, University of California Berkeley, 50 University Hall, 
      Berkeley, CA 94720, USA. Electronic address: SRappaport@Berkeley.edu.
FAU - Metayer, Catherine
AU  - Metayer C
AD  - School of Public Health, University of California Berkeley, 50 University Hall, 
      Berkeley, CA 94720, USA. Electronic address: CMetayer@Berkeley.edu.
LA  - eng
GR  - R01 ES015899/ES/NIEHS NIH HHS/United States
GR  - R01ES009137/ES/NIEHS NIH HHS/United States
GR  - N02CP11015/CP/NCI NIH HHS/United States
GR  - P42 ES004705/ES/NIEHS NIH HHS/United States
GR  - P42ES0470518/ES/NIEHS NIH HHS/United States
GR  - Intramural NIH HHS/United States
GR  - P01ES018172/ES/NIEHS NIH HHS/United States
GR  - P01 ES018172/ES/NIEHS NIH HHS/United States
GR  - R01 ES009137/ES/NIEHS NIH HHS/United States
GR  - R01ES015899/ES/NIEHS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, N.I.H., Intramural
PT  - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20141120
PL  - Netherlands
TA  - Environ Res
JT  - Environmental research
JID - 0147621
RN  - 0 (Dust)
RN  - 0 (Environmental Pollutants)
RN  - 0 (Organic Chemicals)
SB  - IM
MH  - Adult
MH  - California
MH  - *Dust
MH  - Environmental Pollutants/*blood
MH  - Female
MH  - Gas Chromatography-Mass Spectrometry
MH  - Housing
MH  - Humans
MH  - Organic Chemicals/*blood
MH  - Surveys and Questionnaires
PMC - PMC4262624
MID - NIHMS643870
OTO - NOTNLM
OT  - Environmental monitoring
OT  - House dust
OT  - Organochlorine pesticides
OT  - Polybrominated diphenyl ethers
OT  - Polychlorinated biphenyls
EDAT- 2014/12/03 06:00
MHDA- 2015/02/03 06:00
PMCR- 2016/01/01
CRDT- 2014/12/03 06:00
PHST- 2014/07/24 00:00 [received]
PHST- 2014/09/20 00:00 [revised]
PHST- 2014/10/14 00:00 [accepted]
PHST- 2014/12/03 06:00 [entrez]
PHST- 2014/12/03 06:00 [pubmed]
PHST- 2015/02/03 06:00 [medline]
PHST- 2016/01/01 00:00 [pmc-release]
AID - S0013-9351(14)00372-7 [pii]
AID - 10.1016/j.envres.2014.10.009 [doi]
PST - ppublish
SO  - Environ Res. 2015 Jan;136:57-66. doi: 10.1016/j.envres.2014.10.009. Epub 2014 Nov 
      20.