PMID- 25464485
OWN - NLM
STAT- MEDLINE
DCOM- 20150828
LR  - 20220408
IS  - 1874-1754 (Electronic)
IS  - 0167-5273 (Linking)
VI  - 179
DP  - 2015 Jan 20
TI  - Clinical value of assessment of left atrial late gadolinium enhancement in 
      patients undergoing ablation of atrial fibrillation.
PG  - 351-7
LID - S0167-5273(14)02214-1 [pii]
LID - 10.1016/j.ijcard.2014.11.072 [doi]
AB  - BACKGROUND: Left atrial (LA) fibrosis begets atrial fibrillation (AF). 
      Cardiovascular magnetic resonance (CMR) using the late gadolinium enhancement 
      (LGE) technique might visualize the LA fibrosis and thus help to choose an 
      appropriate strategy for treatment of AF. In this regard, we investigated whether 
      the extent of preablation LA LGE would predict AF recurrence after ablation in a 
      non-selected patient population. METHODS: CMR was performed in 95 patients before 
      radiofrequency ablation of AF. An interpretable scan was available in 73 patients 
      (age, 59 +/- 8 years; men, 71%; persistent/paroxysmal AF, 55/45%). The extent of LA 
      LGE was quantified by three established thresholding techniques. In addition, CMR 
      was used to quantify LA volume and reservoir function. The patients were followed 
      for AF recurrence for 1.3 +/- 0.8 years. RESULTS: The arrhythmia recurred in 29 
      (40%) of the patients. The extent of LA LGE did not differ between paroxysmal and 
      persistent AF and it did not predict the AF recurrence. Moreover, the extent of 
      LA LGE did not correlate with LA volume, reservoir function and bipolar voltage. 
      CONCLUSIONS: Our data indicate a limited value of a routine assessment of LA LGE 
      before ablation of AF. Further experimental and clinical researches should be 
      done before applying the method to a wide clinical practice.
CI  - Copyright (c) 2014 Elsevier Ireland Ltd. All rights reserved.
FAU - Sramko, Marek
AU  - Sramko M
AD  - Department of Cardiology, Institute for Clinical and Experimental Medicine 
      (IKEM), Videnska 1958/9, 14021 Prague, Czech Republic. Electronic address: 
      marek.sramko@ikem.cz.
FAU - Peichl, Petr
AU  - Peichl P
AD  - Department of Cardiology, Institute for Clinical and Experimental Medicine 
      (IKEM), Videnska 1958/9, 14021 Prague, Czech Republic.
FAU - Wichterle, Dan
AU  - Wichterle D
AD  - Department of Cardiology, Institute for Clinical and Experimental Medicine 
      (IKEM), Videnska 1958/9, 14021 Prague, Czech Republic.
FAU - Tintera, Jaroslav
AU  - Tintera J
AD  - Department of Radiology, Institute for Clinical and Experimental Medicine (IKEM), 
      Videnska 1958/9, 14021 Prague, Czech Republic.
FAU - Weichet, Jiri
AU  - Weichet J
AD  - Department of Radiology, Na Homolce Hospital, Roentgenova 2/37, 15030 Prague, 
      Czech Republic.
FAU - Maxian, Radoslav
AU  - Maxian R
AD  - Department of Cardiology, Institute for Clinical and Experimental Medicine 
      (IKEM), Videnska 1958/9, 14021 Prague, Czech Republic.
FAU - Pasnisinova, Silvia
AU  - Pasnisinova S
AD  - Department of Cardiology, Institute for Clinical and Experimental Medicine 
      (IKEM), Videnska 1958/9, 14021 Prague, Czech Republic.
FAU - Kockova, Radka
AU  - Kockova R
AD  - Department of Cardiology, Institute for Clinical and Experimental Medicine 
      (IKEM), Videnska 1958/9, 14021 Prague, Czech Republic.
FAU - Kautzner, Josef
AU  - Kautzner J
AD  - Department of Cardiology, Institute for Clinical and Experimental Medicine 
      (IKEM), Videnska 1958/9, 14021 Prague, Czech Republic.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20141107
PL  - Netherlands
TA  - Int J Cardiol
JT  - International journal of cardiology
JID - 8200291
RN  - 0 (Contrast Media)
RN  - 0 (Radioisotopes)
RN  - AU0V1LM3JT (Gadolinium)
SB  - IM
MH  - Aged
MH  - Atrial Fibrillation/*diagnosis/surgery
MH  - *Catheter Ablation/methods
MH  - Contrast Media
MH  - Female
MH  - Follow-Up Studies
MH  - *Gadolinium
MH  - Heart Atria/*pathology/surgery
MH  - Humans
MH  - Magnetic Resonance Imaging, Cine/methods
MH  - Male
MH  - Middle Aged
MH  - *Radioisotopes
OTO - NOTNLM
OT  - Ablation
OT  - Atrial fibrillation
OT  - Fibrosis
OT  - Magnetic resonance imaging
EDAT- 2014/12/03 06:00
MHDA- 2015/09/01 06:00
CRDT- 2014/12/03 06:00
PHST- 2014/08/12 00:00 [received]
PHST- 2014/10/01 00:00 [revised]
PHST- 2014/11/05 00:00 [accepted]
PHST- 2014/12/03 06:00 [entrez]
PHST- 2014/12/03 06:00 [pubmed]
PHST- 2015/09/01 06:00 [medline]
AID - S0167-5273(14)02214-1 [pii]
AID - 10.1016/j.ijcard.2014.11.072 [doi]
PST - ppublish
SO  - Int J Cardiol. 2015 Jan 20;179:351-7. doi: 10.1016/j.ijcard.2014.11.072. Epub 
      2014 Nov 7.