PMID- 25465858 OWN - NLM STAT- MEDLINE DCOM- 20160222 LR - 20141231 IS - 1532-8430 (Electronic) IS - 0022-0736 (Linking) VI - 48 IP - 1 DP - 2015 Jan-Feb TI - Acute electrocardiographic differences between Takotsubo cardiomyopathy and anterior ST elevation myocardial infarction. PG - 79-85 LID - S0022-0736(14)00440-3 [pii] LID - 10.1016/j.jelectrocard.2014.11.001 [doi] AB - BACKGROUND: The aim of this study was to compare ECG findings between anterior ST elevation myocardial infarction (STEMI) and Takotsubo cardiomyopathy (TC) in a similar sample of postmenopausal women. METHODS: Between 2008 and 2011, 27 patients with TC were retrospectively enrolled and matched with 27 STEMI patients with the same age and sex taken from the prospective database of our laboratory. RESULTS: The absence of abnormal Q waves, the ST depression in aVR and the lack of ST elevation in V1 were significantly associated with TC (respectively: 52% vs 18%, p=0.01; 47% vs 11%, p=0.01; 80% vs 41%, p=0.01). The combination of these ECG findings identified TC with a specificity of 95% and a positive predictive value of 85.7%. CONCLUSIONS: The ECG on admission may be useful to distinguish TC from anterior STEMI. The combination of three ECG findings identifies patients with TC with high specificity and positive predictive value. CI - Copyright (c) 2015 Elsevier Inc. All rights reserved. FAU - Mugnai, Giacomo AU - Mugnai G AD - Division of Cardiology, University Hospital of Verona, Verona Italy. Electronic address: mugnai.giacomo@gmail.com. FAU - Pasqualin, Giulia AU - Pasqualin G AD - Division of Cardiology, University Hospital of Verona, Verona Italy. FAU - Benfari, Giovanni AU - Benfari G AD - Division of Cardiology, University Hospital of Verona, Verona Italy. FAU - Bertagnolli, Livio AU - Bertagnolli L AD - Division of Cardiology, University Hospital of Verona, Verona Italy. FAU - Mugnai, Francesca AU - Mugnai F AD - Medicine and Surgery, University of Siena, Siena Italy. FAU - Vassanelli, Francesca AU - Vassanelli F AD - Division of Cardiology, University Hospital of Verona, Verona Italy. FAU - Marchese, Giuseppe AU - Marchese G AD - Division of Cardiology, University Hospital of Verona, Verona Italy. FAU - Pesarini, Gabriele AU - Pesarini G AD - Division of Cardiology, University Hospital of Verona, Verona Italy. FAU - Menegatti, Giuliana AU - Menegatti G AD - Division of Cardiology, University Hospital of Verona, Verona Italy. LA - eng PT - Journal Article DEP - 20141108 PL - United States TA - J Electrocardiol JT - Journal of electrocardiology JID - 0153605 SB - IM CIN - J Electrocardiol. 2015 Mar-Apr;48(2):275-6. PMID: 25582676 MH - Diagnosis, Differential MH - Electrocardiography/*methods MH - Female MH - Humans MH - Male MH - Middle Aged MH - Myocardial Infarction/*diagnosis MH - Reproducibility of Results MH - Sensitivity and Specificity MH - Takotsubo Cardiomyopathy/*diagnosis OTO - NOTNLM OT - Anterior STEMI OT - ECG OT - Myocardial infarction OT - Takotsubo cardiomyopathy EDAT- 2014/12/04 06:00 MHDA- 2016/02/24 06:00 CRDT- 2014/12/04 06:00 PHST- 2014/08/29 00:00 [received] PHST- 2014/12/04 06:00 [entrez] PHST- 2014/12/04 06:00 [pubmed] PHST- 2016/02/24 06:00 [medline] AID - S0022-0736(14)00440-3 [pii] AID - 10.1016/j.jelectrocard.2014.11.001 [doi] PST - ppublish SO - J Electrocardiol. 2015 Jan-Feb;48(1):79-85. doi: 10.1016/j.jelectrocard.2014.11.001. Epub 2014 Nov 8.