PMID- 25471568 OWN - NLM STAT- MEDLINE DCOM- 20150219 LR - 20190718 IS - 1529-2401 (Electronic) IS - 0270-6474 (Print) IS - 0270-6474 (Linking) VI - 34 IP - 49 DP - 2014 Dec 3 TI - When the brain takes a break: a model-based analysis of mind wandering. PG - 16286-95 LID - 10.1523/JNEUROSCI.2062-14.2014 [doi] AB - Mind wandering is an ubiquitous phenomenon in everyday life. In the cognitive neurosciences, mind wandering has been associated with several distinct neural processes, most notably increased activity in the default mode network (DMN), suppressed activity within the anti-correlated (task-positive) network (ACN), and changes in neuromodulation. By using an integrative multimodal approach combining machine-learning techniques with modeling of latent cognitive processes, we show that mind wandering in humans is characterized by inefficiencies in executive control (task-monitoring) processes. This failure is predicted by a single-trial signature of (co)activations in the DMN, ACN, and neuromodulation, and accompanied by a decreased rate of evidence accumulation and response thresholds in the cognitive model. CI - Copyright (c) 2014 the authors 0270-6474/14/3416286-10$15.00/0. FAU - Mittner, Matthias AU - Mittner M AUID- ORCID: 0000-0003-0205-7353 AD - Department of Psychology, University of Tromso, 9037 Tromso, Norway, matthias.mittner@uit.no. FAU - Boekel, Wouter AU - Boekel W AD - Cognitive Science Center Amsterdam, 1018 VZ Amsterdam, The Netherlands. FAU - Tucker, Adrienne M AU - Tucker AM AD - Cognitive Science Center Amsterdam, 1018 VZ Amsterdam, The Netherlands. FAU - Turner, Brandon M AU - Turner BM AD - Stanford University Center for Mind, Brain and Computation, Department of Psychology, Stanford University, Stanford, California 94305. FAU - Heathcote, Andrew AU - Heathcote A AD - Newcastle Cognition Laboratory, School of Psychology, University of Newcastle, 2308 Newcastle, Australia, and. FAU - Forstmann, Birte U AU - Forstmann BU AD - Cognitive Science Center Amsterdam, 1018 VZ Amsterdam, The Netherlands. LA - eng GR - F32 GM103288/GM/NIGMS NIH HHS/United States GR - F32GM103288/GM/NIGMS NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't PL - United States TA - J Neurosci JT - The Journal of neuroscience : the official journal of the Society for Neuroscience JID - 8102140 SB - IM EIN - J Neurosci. 2017 May 31;37(22):5587. PMID: 28566420 MH - Adult MH - Attention/*physiology MH - Brain/*physiology MH - Brain Mapping MH - Cognition/*physiology MH - Executive Function/physiology MH - Female MH - Humans MH - Magnetic Resonance Imaging MH - Male MH - *Models, Neurological MH - Neural Pathways/physiology MH - Pupil/physiology MH - Young Adult PMC - PMC4252543 OTO - NOTNLM OT - MVPA OT - cognitive modeling OT - fMRI OT - mind wandering OT - model-based neuroscience OT - resting state EDAT- 2014/12/05 06:00 MHDA- 2015/02/20 06:00 PMCR- 2015/06/03 CRDT- 2014/12/05 06:00 PHST- 2014/12/05 06:00 [entrez] PHST- 2014/12/05 06:00 [pubmed] PHST- 2015/02/20 06:00 [medline] PHST- 2015/06/03 00:00 [pmc-release] AID - 34/49/16286 [pii] AID - 2062-14 [pii] AID - 10.1523/JNEUROSCI.2062-14.2014 [doi] PST - ppublish SO - J Neurosci. 2014 Dec 3;34(49):16286-95. doi: 10.1523/JNEUROSCI.2062-14.2014.