PMID- 25473730
OWN - NLM
STAT- MEDLINE
DCOM- 20150817
LR  - 20191210
IS  - 1520-5118 (Electronic)
IS  - 0021-8561 (Linking)
VI  - 62
IP  - 51
DP  - 2014 Dec 24
TI  - Development of a surface plasmon resonance immunosensor for detecting melamine in 
      milk products and pet foods.
PG  - 12471-6
LID - 10.1021/jf504055g [doi]
AB  - A sensitive and stable surface plasmon resonance (SPR) immunosensor based on the 
      inhibition format was developed and validated for detecting melamine (MEL) in 
      milk products and pet foods. The sensitivity and the limit of detection (LOD) of 
      the proposed method for MEL were 2.32 x 10(-2) and 1.4 x 10(-3) mug/mL, 
      respectively. The immunosensor was highly specific to MEL, which displayed only 
      low cross-reactivity (CR) (<0.01%) for cyanuric acid, cyanuric chloride, and 
      atrazine. The assay was validated for the detection of MEL in full-cream milk, 
      skim milk powder, infant formula, dog food, and cat food. Most of the recovery 
      results ranged between 76 and 115%. The sensitivities of the assay in each type 
      of sample were 2.57 x 10(-2) mug/mL, 2.32 x 10(-2) mug/kg, 2.51 x 10(-2) mug/kg, 
      2.66 x 10(-2) mug/kg, and 2.68 x 10(-2) mug/kg, respectively, which were much lower 
      than the maximum residue levels (MRLs) of MEL.
FAU - Lu, Yang
AU  - Lu Y
AD  - Key Laboratory of Food Nutrition and Safety, Ministry of Education of China, 
      Tianjin University of Science and Technology , Tianjin 300457, China.
FAU - Xia, Yinqiang
AU  - Xia Y
FAU - Pan, Mingfei
AU  - Pan M
FAU - Wang, Xiaojun
AU  - Wang X
FAU - Wang, Shuo
AU  - Wang S
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20141215
PL  - United States
TA  - J Agric Food Chem
JT  - Journal of agricultural and food chemistry
JID - 0374755
RN  - 0 (Triazines)
RN  - N3GP2YSD88 (melamine)
SB  - IM
MH  - Animal Feed/*analysis
MH  - Animals
MH  - Food Contamination/*analysis
MH  - Immunoassay/instrumentation/*methods
MH  - Infant Formula/*chemistry
MH  - Limit of Detection
MH  - Milk/*chemistry
MH  - Triazines/*analysis
OTO - NOTNLM
OT  - immunosensor
OT  - melamine
OT  - milk
OT  - pet food
OT  - surface plasmon resonance
EDAT- 2014/12/05 06:00
MHDA- 2015/08/19 06:00
CRDT- 2014/12/05 06:00
PHST- 2014/12/05 06:00 [entrez]
PHST- 2014/12/05 06:00 [pubmed]
PHST- 2015/08/19 06:00 [medline]
AID - 10.1021/jf504055g [doi]
PST - ppublish
SO  - J Agric Food Chem. 2014 Dec 24;62(51):12471-6. doi: 10.1021/jf504055g. Epub 2014 
      Dec 15.