PMID- 25476000
OWN - NLM
STAT- MEDLINE
DCOM- 20160121
LR  - 20150309
IS  - 1559-0720 (Electronic)
IS  - 0163-4984 (Linking)
VI  - 164
IP  - 1
DP  - 2015 Mar
TI  - Effects of Cr methionine on glucose metabolism, plasma metabolites, meat lipid 
      peroxidation, and tissue chromium in Mahabadi goat kids.
PG  - 50-7
LID - 10.1007/s12011-014-0190-6 [doi]
AB  - This study was designed to investigate the effects of chromium methionine 
      (Cr-Met) on glucose metabolism, blood metabolites, meat lipid peroxidation, and 
      tissue chromium (Cr) in Mahabadi goat kids. Thirty-two male kids (16.5 +/- 2.8 kg 
      BW, 4-5 months of age) were fed for 90 days in a completely randomized design 
      with four treatments. Treatments were supplemented with 0 (control), 0.5, 1, and 
      1.5 mg Cr as Cr-Met/animal/daily. Blood samples were collected via heparin tubes 
      from the jugular vein on 0, 21, 42, 63, and 90 days of experiment. On day 70, an 
      intravenous glucose tolerance test (IVGTT) was conducted. At the end of the 
      feeding trial, the kids were slaughtered, and the liver, kidney, and longissimus 
      dorsi (LD) muscle samples were collected. Plasma glucose, insulin, and 
      triglyceride concentrations were decreased by Cr supplementation (P < 0.05). LD 
      muscle malondialdehyde (MDA) decreased, and plasma and tissue Cr contents 
      increased with increasing supplemental Cr levels (P < 0.05). Plasma glucose 
      concentrations at 30 and 60 min after glucose infusion were lower in the kids fed 
      1.5 mg Cr diet than the kids fed control diet (P < 0.05). The IVGTT indicated 
      that the kids supplemented with 1.5 mg Cr had higher glucose clearance rate (K) 
      and lower glucose half-life (T(1/2); P < 0.05). Glucose area under the response curve 
      (AUC) from 0 to 180 min after glucose infusion was decreased linearly (P < 0.01) 
      by supplemental Cr. The results suggested that supplemental Cr may improve 
      glucose utilization and lipid oxidation of meat in fattening kid.
FAU - Emami, A
AU  - Emami A
AD  - Department of Animal Science, University of Birjand, Birjand, Iran, 
      ali.emami@ut.ac.ir.
FAU - Ganjkhanlou, M
AU  - Ganjkhanlou M
FAU - Zali, A
AU  - Zali A
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20141206
PL  - United States
TA  - Biol Trace Elem Res
JT  - Biological trace element research
JID - 7911509
RN  - 0 (Blood Glucose)
RN  - 0 (Insulin)
RN  - 0R0008Q3JB (Chromium)
RN  - 4Y8F71G49Q (Malondialdehyde)
RN  - AE28F7PNPL (Methionine)
RN  - IY9XDZ35W2 (Glucose)
SB  - IM
MH  - Animals
MH  - Blood Glucose/drug effects
MH  - Carbohydrate Metabolism/drug effects
MH  - Chromium/*pharmacology
MH  - Glucose/*metabolism
MH  - Glucose Tolerance Test
MH  - Goats
MH  - Insulin/blood
MH  - Lipid Metabolism/drug effects
MH  - Lipid Peroxidation/drug effects
MH  - Male
MH  - Malondialdehyde/metabolism
MH  - Methionine/*pharmacology
EDAT- 2014/12/06 06:00
MHDA- 2016/01/23 06:00
CRDT- 2014/12/06 06:00
PHST- 2014/07/30 00:00 [received]
PHST- 2014/11/19 00:00 [accepted]
PHST- 2014/12/06 06:00 [entrez]
PHST- 2014/12/06 06:00 [pubmed]
PHST- 2016/01/23 06:00 [medline]
AID - 10.1007/s12011-014-0190-6 [doi]
PST - ppublish
SO  - Biol Trace Elem Res. 2015 Mar;164(1):50-7. doi: 10.1007/s12011-014-0190-6. Epub 
      2014 Dec 6.