PMID- 25477914
OWN - NLM
STAT- MEDLINE
DCOM- 20150716
LR  - 20190516
IS  - 1678-4405 (Electronic)
IS  - 1517-8382 (Print)
IS  - 1517-8382 (Linking)
VI  - 45
IP  - 3
DP  - 2014
TI  - In vitro susceptibility to methicillin, vancomycin and linezolid of staphylococci 
      isolated from bloodstream infections in eastern Turkey.
PG  - 829-33
AB  - Staphylococcus species are one of the major causes of bacterial bloodstream 
      infections. Multi-resistant staphylococci infections are major therapeutic 
      problems. This study was aimed to detect methicillin, linezolid and vancomycin 
      susceptibilities of Staphylococcus isolates. A total of 870 Staphylococcus 
      strains isolated from blood cultures of hospitalized patients with BSI. 
      Antimicrobial susceptibilities of methicillin, linezolid and vancomycin were 
      detected according to the Clinical and Laboratory Standards Institute (CLSI). A 
      total of 771 (88.6%) isolates were coagulase-negative staphylococci (CoNS). 700 
      (80.5%) isolates were methicillin-resistant (MR) and 170 (19.5%) were 
      methicillin-susceptible (MS). All the MS isolates were also susceptible to 
      linezolid. However 15 (1.7%) of MR strains were resistant to linezolid. The 
      minimum inhibitory concentration range for the linezolid-resistant isolates by 
      Etest was 6-32 mug/mL. The difference between linezolid susceptibilities for MS 
      and MR staphylococci was not quite statistically significant (p = 0.052). There 
      was no statistically significant difference between S. aureus and CoNS isolates 
      for linezolid susceptibility. All of the isolates were susceptible to vancomycin. 
      In conclusion, linezolid is currently an efficient option for the treatment of 
      methicillin-resistant staphylococci infections.
FAU - Tekin, Alicem
AU  - Tekin A
AD  - Department of Microbiology and Clinical Microbiology Medical Faculty Dicle 
      University Diyarbakir Turkey Department of Microbiology and Clinical 
      Microbiology, Medical Faculty, Dicle University, Diyarbakir, Turkey.
FAU - Dal, Tuba
AU  - Dal T
AD  - Department of Microbiology and Clinical Microbiology Medical Faculty Dicle 
      University Diyarbakir Turkey Department of Microbiology and Clinical 
      Microbiology, Medical Faculty, Dicle University, Diyarbakir, Turkey.
FAU - Deveci, Ozcan
AU  - Deveci O
AD  - Department of Clinical Microbiology and Infectious Diseases Medical Faculty Dicle 
      University Diyarbakir Turkey Department of Clinical Microbiology and Infectious 
      Diseases, Medical Faculty, Dicle University, Diyarbakir, Turkey.
FAU - Tekin, Recep
AU  - Tekin R
AD  - Department of Clinical Microbiology and Infectious Diseases Medical Faculty Dicle 
      University Diyarbakir Turkey Department of Clinical Microbiology and Infectious 
      Diseases, Medical Faculty, Dicle University, Diyarbakir, Turkey.
FAU - Ozcan, Nida
AU  - Ozcan N
AD  - Department of Microbiology and Clinical Microbiology Medical Faculty Dicle 
      University Diyarbakir Turkey Department of Microbiology and Clinical 
      Microbiology, Medical Faculty, Dicle University, Diyarbakir, Turkey.
FAU - Atmaca, Selahattin
AU  - Atmaca S
AD  - Department of Microbiology and Clinical Microbiology Medical Faculty Dicle 
      University Diyarbakir Turkey Department of Microbiology and Clinical 
      Microbiology, Medical Faculty, Dicle University, Diyarbakir, Turkey.
FAU - Dayan, Saim
AU  - Dayan S
AD  - Department of Clinical Microbiology and Infectious Diseases Medical Faculty Dicle 
      University Diyarbakir Turkey Department of Clinical Microbiology and Infectious 
      Diseases, Medical Faculty, Dicle University, Diyarbakir, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20141009
PL  - Brazil
TA  - Braz J Microbiol
JT  - Brazilian journal of microbiology : [publication of the Brazilian Society for 
      Microbiology]
JID - 101095924
RN  - 0 (Acetamides)
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Oxazolidinones)
RN  - 6Q205EH1VU (Vancomycin)
RN  - ISQ9I6J12J (Linezolid)
RN  - Q91FH1328A (Methicillin)
SB  - IM
MH  - Acetamides/*pharmacology
MH  - Anti-Bacterial Agents/*pharmacology
MH  - Drug Resistance, Bacterial
MH  - Humans
MH  - Linezolid
MH  - Methicillin/*pharmacology
MH  - Microbial Sensitivity Tests
MH  - Oxazolidinones/*pharmacology
MH  - Sepsis/*microbiology
MH  - Staphylococcal Infections/*microbiology
MH  - Staphylococcus aureus/*drug effects/isolation & purification
MH  - Turkey
MH  - Vancomycin/*pharmacology
PMC - PMC4204965
OTO - NOTNLM
OT  - Staphylococcus
OT  - linezolid
OT  - methicillin
OT  - vancomycin
EDAT- 2014/12/06 06:00
MHDA- 2015/07/17 06:00
PMCR- 2014/11/09
CRDT- 2014/12/06 06:00
PHST- 2012/12/16 00:00 [received]
PHST- 2013/12/13 00:00 [accepted]
PHST- 2014/12/06 06:00 [entrez]
PHST- 2014/12/06 06:00 [pubmed]
PHST- 2015/07/17 06:00 [medline]
PHST- 2014/11/09 00:00 [pmc-release]
AID - bjm-45-829 [pii]
AID - 10.1590/s1517-83822014000300010 [doi]
PST - epublish
SO  - Braz J Microbiol. 2014 Oct 9;45(3):829-33. doi: 10.1590/s1517-83822014000300010. 
      eCollection 2014.